Skip to main content

VR Adviser, LLC

SEC CIK
0001615982
Latest filing
Aug 14, 2026

Holdings in Q1 2026

Holdings as of Mar 31, 2026, filed May 15, 2026. Long positions only; changes compare share counts with Q4 2025.

Institution overview
Positions
33
+6 vs. Q4 2025
Portfolio value
$2.68B
+$654.6M (+32.3%) vs. Q4 2025
Filed
May 15, 2026
SEC
Holdings of VR Adviser, LLC in Q1 2026
SecurityClassSharesValue% of portfolioShare changeActionHistory
APGEApogee Therapeutics, Inc.COM8,493,321$714.9M26.7%00.0%UnchangedHistory
ERASErasca, Inc.COM16,382,812$265.1M9.9%−1,474,271−8.3%ReducedHistory
ORKAOruka Therapeutics, Inc.COM4,148,428$203.5M7.6%00.0%UnchangedHistory
SYRESpyre Therapeutics, Inc.COM NEW3,685,448$185.9M6.9%00.0%UnchangedHistory
KALVKalVista Pharmaceuticals, Inc.COM6,474,485$130.3M4.9%−254,500−3.8%ReducedHistory
DNTHDianthus Therapeutics, Inc.COM1,180,000$99.0M3.7%+180,000+18.0%AddedHistory
DMRADamora Therapeutics, Inc.COM NEW3,603,595$93.3M3.5%+3,603,595NewHistory
OCULOcular Therapeutix, IncCOM10,346,926$87.6M3.3%+3,031,379+41.4%AddedHistory
COGTCogent Biosciences, Inc.COM2,000,000$77.0M2.9%00.0%UnchangedHistory
VRDNViridian Therapeutics, Inc.COM3,882,709$75.9M2.8%00.0%UnchangedHistory
SVRASavara IncCOM13,740,375$75.0M2.8%00.0%UnchangedHistory
ELVNEnliven Therapeutics, Inc.COM1,726,331$67.7M2.5%−1,500,000−46.5%ReducedHistory
ORICOric Pharmaceuticals, Inc.COM4,319,765$54.7M2.0%−1,356,465−23.9%ReducedHistory
VORVor Biopharma Inc.COM NEW3,041,719$54.3M2.0%+1,097,953+56.5%AddedHistory
MAZEMaze Therapeutics, Inc.COM1,602,034$47.8M1.8%+53,465+3.5%AddedHistory
CTMXCytomX Therapeutics, Inc.COM9,982,124$46.9M1.8%−5,579,376−35.9%ReducedHistory
JBIOJade Biosciences, Inc.COM NEW3,220,364$45.2M1.7%00.0%UnchangedHistory
DYNDyne Therapeutics, Inc.COM2,173,913$39.4M1.5%00.0%UnchangedHistory
CBIOCrescent Biopharma, Inc.COM2,133,576$39.2M1.5%00.0%UnchangedHistory
ZURAZura Bio LtdCLASS A ORD SHS6,434,990$38.3M1.4%+1,089,875+20.4%AddedHistory
RLMDRelmada Therapeutics, Inc.COM4,843,380$33.7M1.3%+4,843,380NewHistory
ENGNenGene Therapeutics Inc.COM4,771,414$32.5M1.2%00.0%UnchangedHistory
TENXTenax Therapeutics, Inc.COM NEW1,675,262$26.8M1.0%+1,675,262NewHistory
ANLAdlai Nortye Group Ltd.ADS3,212,731$22.2M0.8%+3,212,731NewHistory
IPSCCentury Therapeutics, Inc.COM8,695,652$19.7M0.7%+8,695,652NewHistory
CGEMCullinan Therapeutics, Inc.COM1,379,965$19.6M0.7%00.0%UnchangedHistory
HELPCybin Inc.COM NEW3,851,654$18.5M0.7%+11,404+0.3%AddedHistory
SRZNSurrozen, Inc.COM NEW632,931$18.4M0.7%00.0%UnchangedHistory
SEPNSepterna, Inc.COM506,056$12.2M0.5%−104,752−17.1%ReducedHistory
KRROKorro Bio, Inc.COM1,009,500$11.4M0.4%+1,009,500NewHistory
ANROAlto Neuroscience, Inc.COM SHS500,000$11.2M0.4%+500,000NewHistory
ARTVArtiva Biotherapeutics, Inc.COM1,609,569$10.4M0.4%00.0%UnchangedHistory
XFORX4 Pharmaceuticals, IncCOM NEW330,525$1.37M0.1%+330,525NewHistory

Sold out since Q4 2025 (2)

Positions held at the end of Q4 2025 that are gone from this filing.

Positions of VR Adviser, LLC sold out since Q4 2025
SecurityClassShares in Q4 2025Value in Q4 2025% of portfolio in Q4 2025History
UPBUpstream Bio, Inc.COM1,169,298$31.7M1.6%History
CASIFCASI Pharmaceuticals, Inc.ORD SHS987,259$839.2K<0.1%History