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Livermore
Livermore
ZHEN

EcoR1 Capital, LLC

SEC CIK
0001587114
Latest filing
Aug 14, 2026

Holdings in Q2 2021

Holdings as of Jun 30, 2021, filed Aug 16, 2021. Long positions only; changes compare share counts with Q1 2021.

Institution overview
Positions
72
+2 vs. Q1 2021
Portfolio value
$2.66B
+$431.3M (+19.3%) vs. Q1 2021
Filed
Aug 16, 2021
SEC
Holdings of EcoR1 Capital, LLC in Q2 2021
SecurityClassSharesValue% of portfolioShare changeActionHistory
PRTAProthena Corp Public Ltd CoSHS11,284,280$580.1M21.8%+250,000+2.3%AddedHistory
MORFMorphic Holding, Inc.COM3,951,566$226.8M8.5%+952,251+31.7%AddedHistory
ANABAnaptysbio, IncCOM7,521,024$195.0M7.3%+369,400+5.2%AddedHistory
XNCRXencor IncCOM4,906,106$169.2M6.4%+5,800+0.1%AddedHistory
RLAYRelay Therapeutics, Inc.COM4,487,776$164.2M6.2%+1,058,413+30.9%AddedHistory
NUVBNuvation Bio Inc.COM CL A13,711,517$127.7M4.8%+464,500+3.5%AddedHistory
STTKShattuck Labs, Inc.COM3,318,410$96.2M3.6%+860,151+35.0%AddedHistory
RCUSArcus Biosciences, Inc.COM3,335,247$91.6M3.4%+1,139,355+51.9%AddedHistory
ALECAlector, Inc.COM4,242,634$88.4M3.3%+3,640,034+604.1%AddedHistory
SPRYARS Pharmaceuticals, Inc.COM2,618,036$80.9M3.0%+84,401+3.3%AddedHistory
KURAKura Oncology, Inc.COM3,724,437$77.7M2.9%+31,800+0.9%AddedHistory
MRTXMirati Therapeutics, Inc.COM464,298$75.0M2.8%00.0%UnchangedHistory
ORICOric Pharmaceuticals, Inc.COM3,092,218$54.7M2.1%00.0%UnchangedHistory
NRIXNurix Therapeutics, Inc.COM1,967,950$52.2M2.0%−51,069−2.5%ReducedHistory
Avidity Biosciences, Inc.05370A108COM2,103,950$52.0M2.0%00.0%Unchanged–
JANXJanux Therapeutics, Inc.COM1,411,975$35.2M1.3%+1,411,975NewHistory
SLDBSolid Biosciences Inc.COM9,202,702$33.7M1.3%00.0%UnchangedHistory
GRTSGritstone bio, Inc.COM3,421,287$31.2M1.2%00.0%UnchangedHistory
Translate Bio, Inc.89374L104COM1,048,976$28.9M1.1%+452,076+75.7%Added–
ITOSiTeos Therapeutics, Inc.COM1,035,864$26.6M1.0%+775,864+298.4%AddedHistory
EWTXEdgewise Therapeutics, Inc.COM1,224,175$26.1M1.0%00.0%UnchangedHistory
KYMRKymera Therapeutics, Inc.COM519,416$25.2M0.9%+419,416+419.4%AddedHistory
DSGNDesign Therapeutics, Inc.COM1,260,019$25.1M0.9%+122,079+10.7%AddedHistory
AKUSAkouos, Inc.COM1,975,984$24.8M0.9%00.0%UnchangedHistory
ARVNArvinas, Inc.COM321,724$24.8M0.9%+3,020+0.9%AddedHistory
OVIDOvid Therapeutics Inc.COM6,082,200$23.8M0.9%00.0%UnchangedHistory
NGNENeurogene Inc.COM2,358,804$21.8M0.8%−763,900−24.5%ReducedHistory
ACIUAC Immune SASHS2,648,163$21.0M0.8%−1,000,000−27.4%ReducedHistory
BCELAtreca, Inc.CL A COM2,426,685$20.7M0.8%00.0%UnchangedHistory
CNTACentessa Pharmaceuticals plcSPONSORED ADS754,545$16.8M0.6%+754,545NewHistory
KDNYChinook Therapeutics, Inc.COM931,650$13.2M0.5%−318,351−25.5%ReducedHistory
ZNTLZentalis Pharmaceuticals, Inc.COM200,000$10.6M0.4%+200,000NewHistory
CRVSCorvus Pharmaceuticals, Inc.COM3,579,377$9.56M0.4%+3,579,377NewHistory
KRONKronos Bio, Inc.COM387,357$9.28M0.3%00.0%UnchangedHistory
BCTG Acquisition Corp05492W103COM800,000$9.10M0.3%00.0%Unchanged–
KLRSKalaris Therapeutics, Inc.COM447,012$8.82M0.3%00.0%UnchangedHistory
CCCCC4 Therapeutics, Inc.COM STK200,000$7.57M0.3%00.0%UnchangedHistory
KRSAKorsana Biosciences, Inc.COM1,606,276$6.26M0.2%00.0%UnchangedHistory
VERVVerve Therapeutics, Inc.COM100,000$6.03M0.2%+100,000NewHistory
SYRSSyros Pharmaceuticals, Inc.COM1,000,000$5.45M0.2%00.0%UnchangedHistory
JYACJiya Acquisition Corp.COM CL A500,000$4.97M0.2%00.0%UnchangedHistory
ALPNAlpine Immune Sciences, Inc.COM522,635$4.70M0.2%−218,655−29.5%ReducedHistory
DYNDyne Therapeutics, Inc.COM215,000$4.52M0.2%00.0%UnchangedHistory
OBIOOrchestra BioMed Holdings, Inc.ORD SHS400,000$4.08M0.2%00.0%UnchangedHistory
DNTHDianthus Therapeutics, Inc.COM366,867$3.59M0.1%−189,487−34.1%ReducedHistory
IGMSIGM Biosciences, Inc.COM38,030$3.16M0.1%+38,030NewHistory
ODTOdonate Therapeutics, Inc.COM831,200$2.90M0.1%+831,200NewHistory
NGMNGM Biopharmaceuticals IncCOM143,567$2.83M0.1%00.0%UnchangedHistory
FMTXForma Therapeutics Holdings, Inc.SHS105,638$2.63M0.1%+105,638NewHistory
BOLTBolt Biotherapeutics, Inc.COM150,000$2.32M0.1%00.0%UnchangedHistory
BCABBioAtla, Inc.COM50,000$2.12M0.1%00.0%UnchangedHistory
BCLS Acquisition CorpG0904B105COM CL A200,000$2.11M0.1%00.0%Unchanged–
MLTXMoonLake ImmunotherapeuticsCOM CL A200,000$2.07M0.1%00.0%UnchangedHistory
5 01 Acquisition Corp33836P105COM CL A200,000$1.99M0.1%00.0%Unchanged–
Consonance HFW Acquisition CG2445M103SHS CL A200,000$1.99M0.1%+200,000New–
Eucrates Biomedical Acqu CorG3141W106SHS200,000$1.97M0.1%00.0%Unchanged–
FLACFrazier Lifesciences Acquisition CorpCL A SHS200,495$1.96M0.1%+200,495NewHistory
PMVPPMV Pharmaceuticals, Inc.COM50,000$1.71M0.1%00.0%UnchangedHistory
ARYDARYA Sciences Acquisition Corp IVCL A150,000$1.61M0.1%00.0%UnchangedHistory
RPTXRepare Therapeutics Inc.COM50,000$1.56M0.1%00.0%UnchangedHistory
FS Development Corp II30318F100COM CL A150,000$1.50M0.1%00.0%Unchanged–
MGTXMeiraGTx Holdings plcCOM94,819$1.47M0.1%00.0%UnchangedHistory
CareMax, Inc.14171W111*W EXP 06/08/202100,000$1.29M<0.1%+100,000New–
Turmeric Acquisition CorpG9127T108CL A100,000$989.0K<0.1%00.0%Unchanged–
KNTEKinnate Biopharma Inc.COM25,000$582.0K<0.1%00.0%UnchangedHistory
Omega Alpha SpacG6749V107CL A50,000$498.0K<0.1%00.0%Unchanged–
FSTXF-star Therapeutics, Inc.COM46,000$395.0K<0.1%00.0%UnchangedHistory
Nuvation Bio Inc.67080N119*W EXP 07/07/202963,333––00.0%Unchanged–
Consonance HFW Acquisition CG2445M111*W EXP 10/28/20266,665––+66,665New–
Eucrates Biomedical Acqu CorG3141W122*W EXP 10/23/20266,666––00.0%Unchanged–
Frazier Lifesciences Acqu CoG3710A113*W EXP 11/30/20266,665––+66,665New–
Turmeric Acquisition CorpG9127T124*W EXP 10/08/20233,333––00.0%Unchanged–

Sold out since Q1 2021 (11)

Positions held at the end of Q1 2021 that are gone from this filing.

Positions of EcoR1 Capital, LLC sold out since Q1 2021
SecurityClassShares in Q1 2021Value in Q1 2021% of portfolio in Q1 2021History
ELDNEledon Pharmaceuticals, Inc.COM1,115,721$11.9M0.5%History
AMTIApplied Molecular Transport Inc.COM239,443$10.5M0.5%History
LogicBio Therapeutics, Inc.54142F102COM688,700$5.01M0.2%–
WHWKWhitehawk Therapeutics, Inc.COM2,072,782$2.67M0.1%History
Frazier Lifesciences Acqu CoG3710A121UNIT 12/09/2025200,000$2.03M0.1%–
Consonance HFW Acquisition CG2445M129UNIT 99/99/9999200,000$1.95M0.1%–
CDAKCodiak BioSciences, Inc.COM115,195$1.74M0.1%History
SNCEScience 37 Holdings, Inc.COM56,500$573.0K<0.1%History
MTCRMetacrine, Inc.COM62,207$386.0K<0.1%History
Deerfield Healthcare Tech Ac244413118*W EXP 07/16/202100,000–––
Vincerx Pharma, Inc.92731L114*W EXP 12/24/202150,000–––