Skip to main content

Boxer Capital, LLC

SEC CIK
0001465837
Latest filing
Feb 14, 2025

Holdings in Q4 2021

Holdings as of Dec 31, 2021, filed Feb 14, 2022. Long positions only; changes compare share counts with Q3 2021.

Institution overview
Positions
70
−17 vs. Q3 2021
Portfolio value
$2.51B
−$350.1M (−12.2%) vs. Q3 2021
Filed
Feb 14, 2022
SEC
Holdings of Boxer Capital, LLC in Q4 2021
SecurityClassSharesValue% of portfolioShare changeActionHistory
MRTXMirati Therapeutics, Inc.COM2,000,000$293.4M11.7%00.0%UnchangedHistory
State Street SPDR S&P Biotech ETF78464A870ETF2,200,000$246.3M9.8%+2,200,000New–
ITOSiTeos Therapeutics, Inc.COM4,345,016$202.3M8.0%00.0%UnchangedHistory
ONCBeOne Medicines Ltd.ADR500,000$135.5M5.4%−264,188−34.6%ReducedHistory
SWTXSpringWorks Therapeutics, Inc.COM2,075,905$128.7M5.1%00.0%UnchangedHistory
CYTKCytokinetics IncCOM NEW2,100,000$95.7M3.8%00.0%UnchangedHistory
TYRATyra Biosciences, Inc.COM6,448,359$90.7M3.6%+125,000+2.0%AddedHistory
RVMDRevolution Medicines, Inc.COM3,484,264$87.7M3.5%00.0%UnchangedHistory
RLAYRelay Therapeutics, Inc.COM2,669,132$82.0M3.3%+1,375,000+106.2%AddedHistory
TNGXTango Therapeutics, Inc.COM6,871,642$75.2M3.0%00.0%UnchangedHistory
PMVPPMV Pharmaceuticals, Inc.COM2,838,236$65.6M2.6%+570,000+25.1%AddedHistory
MRUSMerus N.V.COM1,900,000$60.4M2.4%00.0%UnchangedHistory
RCUSArcus Biosciences, Inc.COM1,432,200$58.0M2.3%−652,683−31.3%ReducedHistory
BPMCBlueprint Medicines CorpCOM507,374$54.3M2.2%+82,374+19.4%AddedHistory
IDYAIDEAYA Biosciences, Inc.COM2,202,812$52.1M2.1%00.0%UnchangedHistory
SAGESage Therapeutics, Inc.COM1,094,000$46.5M1.9%00.0%UnchangedHistory
ANABAnaptysbio, IncCOM1,300,000$45.2M1.8%00.0%UnchangedHistory
NUVBNuvation Bio Inc.COM CL A4,341,009$36.9M1.5%00.0%UnchangedHistory
NRIXNurix Therapeutics, Inc.COM1,224,892$35.5M1.4%00.0%UnchangedHistory
KNTEKinnate Biopharma Inc.COM1,847,559$32.7M1.3%00.0%UnchangedHistory
RCKTRocket Pharmaceuticals, Inc.COM1,466,051$32.0M1.3%00.0%UnchangedHistory
FATEFate Therapeutics IncCOM500,000$29.3M1.2%+500,000NewHistory
GOSSGossamer Bio, Inc.COM2,462,358$27.8M1.1%00.0%UnchangedHistory
FOLDAmicus Therapeutics, Inc.COM2,325,000$26.9M1.1%00.0%UnchangedHistory
Avidity Biosciences, Inc.05370A108COM1,121,327$26.7M1.1%00.0%Unchanged–
Bellus Health Inc New07987C204COM NEW3,200,000$25.8M1.0%+225,000+7.6%Added–
GHRSGH Research PLCORDINARY SHARES1,013,399$23.6M0.9%00.0%UnchangedHistory
NUVLNuvalent, Inc.COM1,210,192$23.0M0.9%00.0%UnchangedHistory
IOVAIovance Biotherapeutics, Inc.COM1,100,000$21.0M0.8%00.0%UnchangedHistory
DAWNDay One Biopharmaceuticals, Inc.Stock1,189,943$20.1M0.8%00.0%UnchangedHistory
XENEXenon Pharmaceuticals Inc.COM600,000$18.7M0.7%−257,000−30.0%ReducedHistory
ALGSAligos Therapeutics, Inc.COM1,526,048$18.1M0.7%00.0%UnchangedHistory
AKROAkero Therapeutics, Inc.COM831,495$17.6M0.7%00.0%UnchangedHistory
RAREUltragenyx Pharmaceutical Inc.COM200,000$16.8M0.7%+200,000NewHistory
CGEMCullinan Therapeutics, Inc.COM1,074,082$16.6M0.7%00.0%UnchangedHistory
Rain Oncology Inc.75082Q105COM1,175,000$15.1M0.6%00.0%Unchanged–
PRTAProthena Corp Public Ltd CoSHS300,000$14.8M0.6%00.0%UnchangedHistory
MISTMilestone Pharmaceuticals Inc.COM2,238,861$14.7M0.6%−333,333−13.0%ReducedHistory
CNTACentessa Pharmaceuticals plcSPONSORED ADS1,251,137$14.1M0.6%−83,090−6.2%ReducedHistory
PNTPOINT Biopharma Global Inc.COM2,500,000$14.0M0.6%00.0%UnchangedHistory
BCABBioAtla, Inc.COM686,347$13.5M0.5%00.0%UnchangedHistory
THRXTheseus Pharmaceuticals, Inc.COM892,057$11.3M0.5%+892,057NewHistory
BDTXBlack Diamond Therapeutics, Inc.COM2,014,858$10.7M0.4%00.0%UnchangedHistory
RNACCartesian Therapeutics, Inc.COM3,284,072$10.7M0.4%00.0%UnchangedHistory
EPIXESSA Pharma Inc.COM NEW724,500$10.3M0.4%+37,500+5.5%AddedHistory
CDAKCodiak BioSciences, Inc.COM850,065$9.47M0.4%−180,000−17.5%ReducedHistory
NGMNGM Biopharmaceuticals IncCOM500,000$8.86M0.4%00.0%UnchangedHistory
BMEABiomea Fusion, Inc.COM1,188,405$8.85M0.4%−900,000−43.1%ReducedHistory
LITSLite Strategy, Inc.COM NEW2,913,091$7.78M0.3%00.0%UnchangedHistory
EQRXEQRx, Inc.COM1,000,000$6.82M0.3%+1,000,000NewHistory
BCELAtreca, Inc.CL A COM2,202,333$6.67M0.3%00.0%UnchangedHistory
ODTOdonate Therapeutics, Inc.COM4,207,086$5.68M0.2%−1,400,000−25.0%ReducedHistory
SLDBSolid Biosciences Inc.COM3,177,702$5.56M0.2%−556,872−14.9%ReducedHistory
ELEVElevation Acquisition Group Inc.COM872,780$5.25M0.2%−468,750−34.9%ReducedHistory
BCLS Acquisition CorpG0904B105COM CL A500,000$4.90M0.2%00.0%Unchanged–
JYACJiya Acquisition Corp.COM CL A500,000$4.88M0.2%00.0%UnchangedHistory
RACBResearch Alliance Corp. IICOM CL A500,000$4.88M0.2%00.0%UnchangedHistory
Panacea Acquisition Corp. IIG6882C106CL A SHS500,000$4.85M0.2%00.0%Unchanged–
ACADAcadia Pharmaceuticals IncCOM185,000$4.32M0.2%+185,000NewHistory
OBIOOrchestra BioMed Holdings, Inc.ORD SHS400,000$4.03M0.2%00.0%UnchangedHistory
MLTXMoonLake ImmunotherapeuticsCOM CL A400,000$3.96M0.2%00.0%UnchangedHistory
IRONDisc Medicine, Inc.COM1,300,000$3.78M0.2%00.0%UnchangedHistory
DBVTDBV Technologies S.A.SPONSORED ADR2,134,598$3.42M0.1%−5,400,000−71.7%ReducedHistory
ORICOric Pharmaceuticals, Inc.COM200,000$2.94M0.1%00.0%UnchangedHistory
CABACabaletta Bio, Inc.COM540,000$2.05M0.1%−1,063,361−66.3%ReducedHistory
Omega Alpha SpacG6749V107CL A200,000$1.95M0.1%00.0%Unchanged–
TARAProtara Therapeutics, Inc.COM STK209,227$1.41M0.1%00.0%UnchangedHistory
GNCAGenocea Biosciences, Inc.COM NEW1,134,453$1.32M0.1%00.0%UnchangedHistory
SRZNSurrozen, Inc.COM200,000$1.29M0.1%00.0%UnchangedHistory
Nuvation Bio Inc.67080N119*W EXP 07/07/202266,666$504.0K<0.1%00.0%Unchanged–

Options (1)

Puts and calls in the same filing. Amounts are the market value of the underlying shares, which is what 13F reports.

Option positions of Boxer Capital, LLC in Q4 2021
SecurityClassPutsCalls
SPDR Ser Tr78464A900CALL–$61.6M

Sold out since Q3 2021 (23)

Positions held at the end of Q3 2021 that are gone from this filing.

Positions of Boxer Capital, LLC sold out since Q3 2021
SecurityClassShares in Q3 2021Value in Q3 2021% of portfolio in Q3 2021History
ARGXArgenx SESPONSORED ADR170,926$51.6M1.8%History
CNTBConnect Biopharma Holdings LtdADS2,081,323$50.4M1.8%History
SNDXSyndax Pharmaceuticals IncCOM2,287,782$43.7M1.5%History
FULCFulcrum Therapeutics, Inc.COM1,250,000$35.3M1.2%History
TPTXTurning Point Therapeutics, Inc.COM525,000$34.9M1.2%History
MRNSMarinus Pharmaceuticals, Inc.COM NEW2,400,000$27.3M1.0%History
KURAKura Oncology, Inc.COM1,050,289$19.7M0.7%History
PASGPassage BIO, Inc.COM1,928,315$19.2M0.7%History
SPRYARS Pharmaceuticals, Inc.COM1,675,377$16.7M0.6%History
FSTXF-star Therapeutics, Inc.COM1,751,428$12.8M0.4%History
Achilles Therapeutics PLC00449L102SPONSORED ADS1,536,016$12.0M0.4%–
NGNENeurogene Inc.COM1,501,058$10.9M0.4%History
TLISTalis Biomedical CorpCOM1,550,998$9.69M0.3%History
IMMPIMMUTEP LtdSPONSORED ADS2,500,000$9.68M0.3%History
ERASErasca, Inc.COM450,000$9.55M0.3%History
VINCVincerx Pharma, Inc.COM NEW450,000$7.28M0.3%History
ASMBAssembly Biosciences, Inc.COM1,500,000$5.22M0.2%History
NAUTNautilus Biotechnology, Inc.COM750,000$4.61M0.2%History
LJPCLa Jolla Pharmaceutical CoCOM PAR $.0001 2890,700$3.55M0.1%History
KNSAKiniksa Pharmaceuticals International, plcCOM CL A290,577$3.31M0.1%History
Direxion Shs ETF Tr25460G716DAILY S&P BIOTEC150,000$3.19M0.1%–
SNCEScience 37 Holdings, Inc.COM200,000$1.96M0.1%History
CLRBCellectar Biosciences, Inc.COM PAR920,000$851.0K<0.1%History