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Great Point Partners LLC

SEC CIK
0001281446
Latest filing
Aug 14, 2026

Holdings in Q2 2026

Holdings as of Jun 30, 2026, filed Aug 14, 2026. Long positions only; changes compare share counts with Q1 2026.

Institution overview
Positions
37
−2 vs. Q1 2026
Portfolio value
$424.4M
+$16.2M (+4.0%) vs. Q1 2026
Filed
Aug 14, 2026
SEC
Holdings of Great Point Partners LLC in Q2 2026
SecurityClassSharesValue% of portfolioShare changeActionHistory
VORVor Biopharma Inc.COM NEW1,700,000$31.3M7.4%−50,000−2.9%ReducedHistory
ABVXAbivax S.A.SPONSORED ADS204,314$27.2M6.4%+204,314NewHistory
VERAVera Therapeutics, Inc.CL A600,836$25.8M6.1%+401,488+201.4%AddedHistory
ZURAZura Bio LtdCLASS A ORD SHS4,215,930$24.9M5.9%00.0%UnchangedHistory
ALMSAlumis Inc.COM856,061$24.1M5.7%00.0%UnchangedHistory
SLGLSol-Gel Technologies Ltd.SHS NEW274,363$20.3M4.8%00.0%UnchangedHistory
DFTXDefinium Therapeutics, Inc.COM SHS425,000$20.0M4.7%+425,000NewHistory
ANNXAnnexon, Inc.COM3,500,000$20.0M4.7%+1,000,000+40.0%AddedHistory
ORKAOruka Therapeutics, Inc.COM183,330$17.4M4.1%00.0%UnchangedHistory
MLTXMoonLake ImmunotherapeuticsCLASS A ORD855,813$16.7M3.9%+355,813+71.2%AddedHistory
SGMTSagimet Biosciences Inc.COM SER A2,029,933$15.7M3.7%+2,029,933NewHistory
CTNMContineum Therapeutics, Inc.CL A921,481$15.1M3.6%+121,283+15.2%AddedHistory
IMMXImmix Biopharma, Inc.COM1,277,642$13.2M3.1%+927,642+265.0%AddedHistory
CLYMClimb Bio, Inc.COM1,000,000$13.0M3.1%−334,130−25.0%ReducedHistory
AMLXAmylyx Pharmaceuticals, Inc.COM700,000$12.6M3.0%−1,050,000−60.0%ReducedHistory
NKTRNektar TherapeuticsCOM NEW175,000$12.2M2.9%−141,453−44.7%ReducedHistory
NGNENeurogene Inc.COM352,180$11.1M2.6%−147,820−29.6%ReducedHistory
LBRXLB Pharmaceuticals IncCOM SHS317,221$10.3M2.4%+17,221+5.7%AddedHistory
IRDOpus Genetics, Inc.COM1,970,187$8.10M1.9%+1,645,847+507.4%AddedHistory
EPRXEupraxia Pharmaceuticals Inc.COM1,200,000$7.93M1.9%00.0%UnchangedHistory
DRUGBright Minds Biosciences Inc.COM NEW109,603$7.69M1.8%−110,397−50.2%ReducedHistory
IFRXInflaRx N.V.COM3,046,557$6.82M1.6%+3,046,557NewHistory
RLMDRelmada Therapeutics, Inc.COM842,106$5.83M1.4%00.0%UnchangedHistory
JATTJATT II Acquisition Corp.ORD SHS500,000$5.68M1.3%+500,000NewHistory
CGEMCullinan Therapeutics, Inc.COM300,000$5.46M1.3%00.0%UnchangedHistory
ALTAltimmune, Inc.COM NEW1,741,232$5.29M1.2%+1,741,232NewHistory
AMANAmanat Acquisition Corp.CL A ORD500,000$5.08M1.2%+500,000NewHistory
RZLTRezolute, Inc.COM NEW951,809$4.95M1.2%00.0%UnchangedHistory
SLNSilence Therapeutics plcADS450,000$4.94M1.2%−570,489−55.9%ReducedHistory
PALIPalisade Bio, Inc.COM2,284,819$4.78M1.1%−1,120,938−32.9%ReducedHistory
EVMNEvommune, Inc.COM SHS325,000$4.32M1.0%00.0%UnchangedHistory
SCYXScynexis IncCOM944,292$3.84M0.9%00.0%UnchangedConverted for a 1-for-8 splitHistory
ELVNEnliven Therapeutics, Inc.COM70,000$3.55M0.8%+70,000NewHistory
HUMAHumacyte, Inc.COM3,750,000$2.93M0.7%00.0%UnchangedHistory
RNTXRein Therapeutics, Inc.COM NEW2,575,000$2.68M0.6%+2,575,000NewHistory
DBVTDBV Technologies S.A.SPONSORED ADS156,906$2.57M0.6%+156,906NewHistory
PMNProMIS Neurosciences Inc.COM SHS86,150$1.13M0.3%−285,252−76.8%ReducedHistory

Options (5)

Puts and calls in the same filing. Amounts are the market value of the underlying shares, which is what 13F reports.

Option positions of Great Point Partners LLC in Q2 2026
SecurityClassPutsCalls
ABVXAbivax S.A.SPONSORED ADS–$53.3M
IBRXImmunityBio, Inc.COM$26.3M–
RAREUltragenyx Pharmaceutical Inc.COM$20.0M–
GALTGalectin Therapeutics IncCOM NEW–$3.71M
AVXLAnavex Life Sciences Corp.COM NEW–$1.35M

Sold out since Q1 2026 (12)

Positions held at the end of Q1 2026 that are gone from this filing.

Positions of Great Point Partners LLC sold out since Q1 2026
SecurityClassShares in Q1 2026Value in Q1 2026% of portfolio in Q1 2026History
APGEApogee Therapeutics, Inc.COM374,000$31.5M7.7%History
KALVKalVista Pharmaceuticals, Inc.COM675,000$13.6M3.3%History
IMVTImmunovant, Inc.COM545,625$13.6M3.3%History
JBIOJade Biosciences, Inc.COM NEW964,462$13.6M3.3%History
ZBIOZenas BioPharma, Inc.COM524,066$10.2M2.5%History
CMPXCompass Therapeutics, Inc.COM1,350,000$7.14M1.7%History
CNTXContext Therapeutics Inc.COM2,238,496$5.86M1.4%History
UNCYUnicycive Therapeutics, Inc.COM NEW796,558$5.24M1.3%History
TENXTenax Therapeutics, Inc.COM NEW327,307$5.23M1.3%History
PHVSPharvaris N.V.COM82,800$2.34M0.6%History
AVTXAvalo Therapeutics, Inc.COM NEW124,666$1.86M0.5%History
ALKSAlkermes plc.SHS50,000$1.77M0.4%History