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Perceptive Advisors LLC

SEC CIK
0001224962
Latest filing
Aug 14, 2026

Holdings in Q4 2025

Holdings as of Dec 31, 2025, filed Feb 17, 2026. Long positions only; changes compare share counts with Q3 2025.

Institution overview
Positions
112
+21 vs. Q3 2025
Portfolio value
$5.46B
+$2.00B (+57.7%) vs. Q3 2025
Filed
Feb 17, 2026
SEC
Holdings of Perceptive Advisors LLC in Q4 2025
SecurityClassSharesValue% of portfolioShare changeActionHistory
IMMXImmix Biopharma, Inc.COM338,941$1.77M<0.1%+338,941NewHistory
LXEOLexeo Therapeutics, Inc.COM139,835$1.39M<0.1%00.0%UnchangedHistory
CPIXCumberland Pharmaceuticals IncCOM341,087$1.36M<0.1%+341,087NewHistory
MDLNMedline Inc.COM CL A28,000$1.18M<0.1%+28,000NewHistory
PTNPalatin Technologies IncCOM NEW70,000$1.08M<0.1%+70,000NewHistory
LENZLENZ Therapeutics, Inc.COM50,000$800.0K<0.1%+50,000NewHistory
BDSXBiodesix IncCOM108,694$739.1K<0.1%00.0%UnchangedHistory
NVNOenVVeno Medical CorpCOMMON STOCK1,759,035$564.3K<0.1%00.0%UnchangedHistory
IOVAIovance Biotherapeutics, Inc.COM152,714$416.9K<0.1%+152,714NewHistory
RVMDWRevolution Medicines, Inc.*W EXP 12/17/202250,000$235.0K<0.1%00.0%UnchangedHistory
ENSCEnsysce Biosciences, Inc.COM NEW86,666$79.7K<0.1%00.0%UnchangedHistory
Surrozen, Inc.86889P117*W EXP 08/01/203166,666$3.33K<0.1%00.0%Unchanged–

Options (4)

Puts and calls in the same filing. Amounts are the market value of the underlying shares, which is what 13F reports.

Option positions of Perceptive Advisors LLC in Q4 2025
SecurityClassPutsCalls
State Street SPDR S&P Biotech ETF78464A870ETF$134.1M–
CAPRCapricor Therapeutics, Inc.COM NEW–$6.99M
BHVNBiohaven Ltd.COM–$5.64M
TECXTectonic Therapeutic, Inc.COM–$5.21M

Sold out since Q3 2025 (14)

Positions held at the end of Q3 2025 that are gone from this filing.

Positions of Perceptive Advisors LLC sold out since Q3 2025
SecurityClassShares in Q3 2025Value in Q3 2025% of portfolio in Q3 2025History
MRUSMerus N.V.COM1,353,093$127.4M3.7%History
INSMINSMED IncCOM PAR $.01702,130$101.1M2.9%History
VRNAVerona Pharma plcSPONSORED ADS524,088$55.9M1.6%History
AKROAkero Therapeutics, Inc.COM1,135,766$53.9M1.6%History
JANXJanux Therapeutics, Inc.COM292,686$7.15M0.2%History
TEMTempus AI, Inc.CL A85,000$6.86M0.2%History
HTFLHeartflow, Inc.COM150,000$5.05M0.1%History
SCPHscPharmaceuticals Inc.COM583,142$3.31M0.1%History
VKTXViking Therapeutics, Inc.COM105,597$2.78M0.1%History
PYXSPyxis Oncology, Inc.COMMON STOCK1,178,307$2.62M0.1%History
TRIBTrinity Biotech PLCSPONS ADR NEW1,790,000$1.86M0.1%History
LYRALyra Therapeutics, Inc.COM NEW229,382$1.50M<0.1%History
QUREuniQure N.V.SHS20,000$1.17M<0.1%History
APYXApyx Medical CorpCOM150,000$321.0K<0.1%History