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Artal Group S.A.

SEC CIK
0001053906
Latest filing
Aug 13, 2026

Holdings in Q1 2024

Holdings as of Mar 31, 2024, filed May 17, 2024. Long positions only; changes compare share counts with Q4 2023.

Institution overview
Positions
107
+16 vs. Q4 2023
Portfolio value
$3.88B
+$946.7M (+32.3%) vs. Q4 2023
Filed
May 17, 2024
AmendedSEC
Holdings of Artal Group S.A. in Q1 2024
SecurityClassSharesValue% of portfolioShare changeActionHistory
CAVACava Group, Inc.COM26,507,990$1.86B47.9%−5,500,000−17.2%ReducedHistory
LXRXLexicon Pharmaceuticals, Inc.COM NEW117,553,284$282.1M7.3%00.0%UnchangedHistory
SRRKScholar Rock Holding CorpCOM11,259,438$200.0M5.2%00.0%UnchangedHistory
KYMRKymera Therapeutics, Inc.COM3,027,135$121.7M3.1%+496,400+19.6%AddedHistory
ARWRArrowhead Pharmaceuticals, Inc.COM3,036,668$86.8M2.2%+2,008,413+195.3%AddedHistory
MORFMorphic Holding, Inc.COM2,213,188$77.9M2.0%+75,000+3.5%AddedHistory
APLSApellis Pharmaceuticals, Inc.COM1,315,282$77.3M2.0%−106,064−7.5%ReducedHistory
SWTXSpringWorks Therapeutics, Inc.COM1,415,348$69.7M1.8%−200,000−12.4%ReducedHistory
CRNXCrinetics Pharmaceuticals, Inc.COM1,390,477$65.1M1.7%+1,390,477NewHistory
ONCBeOne Medicines Ltd.ADR404,782$63.3M1.6%+302+0.1%AddedHistory
SLNSilence Therapeutics plcADS2,779,619$60.0M1.5%−220,381−7.3%ReducedHistory
DYNDyne Therapeutics, Inc.COM1,517,960$43.1M1.1%+300,000+24.6%AddedHistory
RVMDRevolution Medicines, Inc.COM1,318,649$42.5M1.1%−377,300−22.2%ReducedHistory
KURAKura Oncology, Inc.COM1,919,884$41.0M1.1%+151,828+8.6%AddedHistory
NMRANeumora Therapeutics, Inc.COM2,924,052$40.2M1.0%+371,350+14.5%AddedHistory
KRROKorro Bio, Inc.COM419,226$37.7M1.0%+621+0.1%AddedHistory
CYTKCytokinetics IncCOM NEW506,584$35.5M0.9%−707,700−58.3%ReducedHistory
SLDBSolid Biosciences Inc.COM NEW2,500,000$33.3M0.9%+1,590,781+175.0%AddedHistory
IGMSIGM Biosciences, Inc.COM3,080,422$29.7M0.8%−20,000−0.6%ReducedHistory
MDGLMadrigal Pharmaceuticals, Inc.COM110,507$29.5M0.8%+110,507NewHistory
CBIOCrescent Biopharma, Inc.COM8,589,064$25.8M0.7%00.0%UnchangedHistory
WVEWave Life Sciences, Inc.SHS4,051,400$25.0M0.6%+1,044,000+34.7%AddedHistory
PRTAProthena Corp Public Ltd CoSHS1,001,360$24.8M0.6%+500,000+99.7%AddedHistory
VERAVera Therapeutics, Inc.CL A506,019$21.8M0.6%+506,019NewHistory
VKTXViking Therapeutics, Inc.COM253,863$20.8M0.5%+253,863NewHistory
MRUSMerus N.V.COM455,081$20.5M0.5%+455,081NewHistory
NAMSNewAmsterdam Pharma Co N.V.ORDINARY SHARES800,000$18.9M0.5%+800,000NewHistory
TNGXTango Therapeutics, Inc.COM2,194,841$17.4M0.4%+2,194,841NewHistory
SLRNACELYRIN, Inc.COM2,405,143$16.2M0.4%−630,745−20.8%ReducedHistory
ALPNAlpine Immune Sciences, Inc.COM405,784$16.1M0.4%+355,025+699.4%AddedHistory
CNTACentessa Pharmaceuticals plcSPONSORED ADS1,412,500$16.0M0.4%+400,000+39.5%AddedHistory
GOSSGossamer Bio, Inc.COM13,308,968$15.7M0.4%+1,250,000+10.4%AddedHistory
EWTXEdgewise Therapeutics, Inc.COM811,718$14.8M0.4%+811,718NewHistory
SYRSSyros Pharmaceuticals, Inc.COM NEW2,505,013$13.4M0.3%00.0%UnchangedHistory
SESea LtdSPONSORD ADS237,500$12.8M0.3%−134,500−36.2%ReducedHistory
LXEOLexeo Therapeutics, Inc.COM801,716$12.6M0.3%+198,281+32.9%AddedHistory
ATXSAstria Therapeutics, Inc.COM884,214$12.4M0.3%+884,214NewHistory
FOLDAmicus Therapeutics, Inc.COM1,011,776$11.9M0.3%−1,014,588−50.1%ReducedHistory
GBIOGeneration Bio Co.COM2,830,591$11.5M0.3%+16,400+0.6%AddedHistory
XENEXenon Pharmaceuticals Inc.COM253,387$10.9M0.3%+253,387NewHistory
CLDXCelldex Therapeutics, Inc.COM NEW253,000$10.6M0.3%+253,000NewHistory
TSHATaysha Gene Therapies, Inc.COM SHS3,687,548$10.6M0.3%+24,444+0.7%AddedHistory
DNLIDenali Therapeutics Inc.COM502,899$10.3M0.3%−300,000−37.4%ReducedHistory
APGEApogee Therapeutics, Inc.COM152,500$10.1M0.3%+152,500NewHistory
ERASErasca, Inc.COM4,721,194$9.73M0.3%00.0%UnchangedHistory
AGENAgenus IncCOM NEW15,631,235$9.07M0.2%00.0%UnchangedHistory
SEERSeer, Inc.COM CL A4,750,000$9.03M0.2%00.0%UnchangedHistory
RAREUltragenyx Pharmaceutical Inc.COM177,932$8.31M0.2%+177,932NewHistory
ELEVElevation Acquisition Group Inc.COM1,513,015$7.76M0.2%+1,513,015NewHistory
OVIDOvid Therapeutics Inc.COM2,500,000$7.63M0.2%00.0%UnchangedHistory
TRMLTourmaline Bio, Inc.COM314,496$7.20M0.2%+223,070+244.0%AddedHistory
APLTApplied Therapeutics, Inc.COM1,009,500$6.86M0.2%+1,009,500NewHistory
PDDPDD Holdings Inc.SPONSORED ADS56,500$6.57M0.2%+24,000+73.8%AddedHistory
GPCRStructure Therapeutics Inc.SPONSORED ADS151,780$6.51M0.2%+65,180+75.3%AddedHistory
VIGLVigil Neuroscience, Inc.COM1,811,191$6.18M0.2%00.0%UnchangedHistory
AXSMAxsome Therapeutics, Inc.COM76,837$6.13M0.2%+76,837NewHistory
RNACCartesian Therapeutics, Inc.COM9,136,635$5.94M0.2%00.0%UnchangedHistory
ANROAlto Neuroscience, Inc.COM SHS350,000$5.37M0.1%+350,000NewHistory
BDTXBlack Diamond Therapeutics, Inc.COM1,046,517$5.31M0.1%−1,000,000−48.9%ReducedHistory
RGNXREGENXBIO Inc.COM250,000$5.27M0.1%+250,000NewHistory
KLRSKalaris Therapeutics, Inc.COM6,597,167$4.98M0.1%00.0%UnchangedHistory
KYTXKyverna Therapeutics, Inc.COM200,000$4.97M0.1%+200,000NewHistory
FHTXFoghorn Therapeutics Inc.COM720,720$4.84M0.1%00.0%UnchangedHistory
OMGAOmega Therapeutics, Inc.COMMON STOCK1,323,530$4.83M0.1%00.0%UnchangedHistory
TSMTaiwan Semiconductor Manufacturing Co LtdADR32,000$4.35M0.1%−35,999−52.9%ReducedHistory
GERNGeron CorpCOM1,281,194$4.23M0.1%+1,281,194NewHistory
STOKStoke Therapeutics, Inc.COM300,000$4.05M0.1%+300,000NewHistory
HOOKHOOKIPA Pharma Inc.COM5,666,410$4.03M0.1%00.0%UnchangedHistory
SGMTSagimet Biosciences Inc.COM SER A724,771$3.93M0.1%−200,000−21.6%ReducedHistory
BEKEKE Holdings Inc.SPONSORED ADS275,000$3.78M0.1%+25,000+10.0%AddedHistory
RPTXRepare Therapeutics Inc.COM700,000$3.30M0.1%00.0%UnchangedHistory
MGXMetagenomi Therapeutics, Inc.COM300,000$3.17M0.1%+300,000NewHistory
PEPGPepGen Inc.COM200,000$2.94M0.1%+200,000NewHistory
ADAGAdagene Inc.ADS1,020,000$2.86M0.1%+20,000+2.0%AddedHistory
GRTSGritstone bio, Inc.COM1,030,952$2.65M0.1%+1,030,952NewHistory
FATEFate Therapeutics IncCOM360,311$2.64M0.1%+360,311NewHistory
VORVor Biopharma Inc.COM1,000,000$2.37M0.1%−1,347,424−57.4%ReducedHistory
AMZNAmazon Com IncStock12,000$2.16M0.1%00.0%UnchangedHistory
JANXJanux Therapeutics, Inc.COM50,000$1.88M<0.1%+50,000NewHistory
NVDANVIDIA CorpStock1,900$1.72M<0.1%+1,900NewHistory
AAPLApple Inc.Stock10,000$1.71M<0.1%+10,000NewHistory
DTDynatrace, Inc.Stock36,000$1.67M<0.1%+36,000NewHistory
ADBEAdobe Inc.Stock3,100$1.56M<0.1%+3,100NewHistory
EDUNew Oriental Education & Technology Group Inc.SPON ADR15,000$1.30M<0.1%+15,000NewHistory
DDOGDatadog, Inc.CL A COM9,600$1.19M<0.1%+2,100+28.0%AddedHistory
KRONKronos Bio, Inc.COM842,954$1.10M<0.1%00.0%UnchangedHistory
GOOGLAlphabet Inc.Stock7,000$1.06M<0.1%−800−10.3%ReducedHistory
MSFTMicrosoft CorpStock2,500$1.05M<0.1%00.0%UnchangedHistory
SNOWSnowflake Inc.Stock6,500$1.05M<0.1%+6,500NewHistory
INTAIntapp, Inc.COM29,500$1.01M<0.1%+12,000+68.6%AddedHistory
IRWDIronwood Pharmaceuticals IncCOM CL A110,532$962.7K<0.1%00.0%UnchangedHistory
Achilles Therapeutics PLC00449L102SPONSORED ADS755,375$944.2K<0.1%−1,500,000−66.5%Reduced–
PANWPalo Alto Networks IncStock3,000$852.4K<0.1%+3,000NewHistory
AMDAdvanced Micro Devices IncStock4,500$812.2K<0.1%+2,000+80.0%AddedHistory
PCORProcore Technologies, Inc.COM9,500$780.6K<0.1%00.0%UnchangedHistory
PEGAPegasystems IncCOM11,500$743.4K<0.1%00.0%UnchangedHistory
MDBMongoDB, Inc.CL A2,000$717.3K<0.1%+1,000+100.0%AddedHistory
VVisa Inc.Stock2,500$697.7K<0.1%00.0%UnchangedHistory
PYPLPayPal Holdings, Inc.Stock10,000$669.9K<0.1%+5,000+100.0%AddedHistory
CFLTConfluent, Inc.CLASS A COM19,000$579.9K<0.1%00.0%UnchangedHistory

Options (4)

Puts and calls in the same filing. Amounts are the market value of the underlying shares, which is what 13F reports.

Option positions of Artal Group S.A. in Q1 2024
SecurityClassPutsCalls
State Street SPDR S&P Biotech ETF78464A870ETF–$23.7M
ARWRArrowhead Pharmaceuticals, Inc.COM–$17.2M
PYPLPayPal Holdings, Inc.Stock–$3.89M
GOSSGossamer Bio, Inc.COM–$244.3K

Sold out since Q4 2023 (18)

Positions held at the end of Q4 2023 that are gone from this filing.

Positions of Artal Group S.A. sold out since Q4 2023
SecurityClassShares in Q4 2023Value in Q4 2023% of portfolio in Q4 2023History
ARGXArgenx SESPONSORED ADR116,388$44.3M1.5%History
HARPHarpoon Therapeutics, Inc.COM NEW1,304,127$14.8M0.5%History
NTRANatera, Inc.COM200,000$12.5M0.4%History
ROIVRoivant Sciences Ltd.SHS1,000,000$11.2M0.4%History
SDGRSchrodinger, Inc.COM300,000$10.7M0.4%History
FUSNFusion Pharmaceuticals Inc.COM1,005,500$9.66M0.3%History
CBAYCymaBay Therapeutics, Inc.COM303,600$7.17M0.2%History
ITOSiTeos Therapeutics, Inc.COM400,000$4.38M0.1%History
REPLReplimune Group, Inc.COM500,000$4.21M0.1%History
IMAImageneBio, Inc.COM999,513$1.97M0.1%History
BZKanzhun LtdSPONSORED ADS100,000$1.66M0.1%History
CRISCuris IncCOM105,000$1.34M<0.1%History
MEHCQChrome Holding Co.CLASS A COM661,009$604.0K<0.1%History
LLYEli Lilly & CoStock1,000$583.0K<0.1%History
RELYRemitly Global, Inc.COM25,000$486.0K<0.1%History
XLOXilio Therapeutics, Inc.COM450,000$248.0K<0.1%History
CERECerevel Therapeutics Holdings, Inc.COM5,041$214.0K<0.1%History
SNTISenti Biosciences Holdings, Inc.COM55,555$37.0K<0.1%History