| Date | Insider | Title | Code | Shares | Price | Value |
|---|---|---|---|---|---|---|
| Aug 17, 2026 | Hill Emily Luisa | Chief Financial Officer | S | 9,256 | $14.2800 | $132.18K |
| Aug 11, 2026 | BAKER BROS. ADVISORS LP | Director, 10% Owner | P | 2,609,946 | $12.0599 | $31.48M |
| Aug 11, 2026 | BAKER BROS. ADVISORS LP | Director, 10% Owner | P | 126,394 | $12.0599 | $1.52M |
| Aug 10, 2026 | Schwendenman Andrew | Chief Accounting Officer | S | 7,632 | $12.9700 | $98.99K |
| Aug 10, 2026 | Xynos Konstantinos | Chief Medical Officer | S | 11,447 | $12.9700 | $148.47K |
| Aug 10, 2026 | Hill Emily Luisa | Chief Financial Officer | S | 11,448 | $12.9700 | $148.48K |
| Aug 10, 2026 | Patel Sushil | Chief Executive Officer | S | 39,341 | $12.9700 | $510.25K |
| Jun 1, 2026 | Sarchi Christopher | Chief Commercial Officer | S | 12,000 | $9.2400 | $110.88K |
| May 18, 2026 | Hill Emily Luisa | Chief Financial Officer | S | 7,812 | $5.0800 | $39.68K |
| May 18, 2026 | Patel Sushil | Chief Executive Officer | S | 37,324 | $5.0800 | $189.60K |
| May 18, 2026 | Astley-Sparke Philip | Director | S | 17,657 | $5.0800 | $89.70K |
| May 18, 2026 | Sarchi Christopher | Chief Commercial Officer | S | 8,626 | $5.0800 | $43.82K |
| May 18, 2026 | Schwendenman Andrew | Chief Accounting Officer | S | 7,894 | $5.0800 | $40.10K |
| May 18, 2026 | Xynos Konstantinos | Chief Medical Officer | S | 14,023 | $5.0800 | $71.24K |
| Apr 2, 2026 | Sarchi Christopher | Chief Commercial Officer | S | 6,500 | $8.0100 | $52.06K |
| Apr 1, 2026 | Peeples-Dyer Veleka | Director | A | 44,500 | $0.0000 | $0.00 |
| Apr 1, 2026 | Hill Emily Luisa | Chief Financial Officer | A | 75,000 | $0.0000 | $0.00 |
| Apr 1, 2026 | Hill Emily Luisa | Chief Financial Officer | A | 50,000 | $0.0000 | $0.00 |
| Apr 1, 2026 | Weinand Dieter | Director | A | 44,500 | $0.0000 | $0.00 |
| Apr 1, 2026 | Pucci Paolo | Director | A | 44,500 | $0.0000 | $0.00 |
| Apr 1, 2026 | SLATTERY JOSEPH P | Director | A | 44,500 | $0.0000 | $0.00 |
| Apr 1, 2026 | Schwendenman Andrew | Chief Accounting Officer | A | 55,000 | $0.0000 | $0.00 |
| Apr 1, 2026 | Schwendenman Andrew | Chief Accounting Officer | A | 36,667 | $0.0000 | $0.00 |
| Apr 1, 2026 | Dhingra Kapil | Director | A | 44,500 | $0.0000 | $0.00 |
| Apr 1, 2026 | Patel Sushil | Chief Executive Officer | A | 376,860 | $0.0000 | $0.00 |
| Apr 1, 2026 | Patel Sushil | Chief Executive Officer | A | 251,240 | $0.0000 | $0.00 |
| Apr 1, 2026 | Oliger Christy J. | Director | A | 44,500 | $0.0000 | $0.00 |
| Apr 1, 2026 | Balachandran Madhavan | Director | A | 44,500 | $0.0000 | $0.00 |
| Apr 1, 2026 | Xynos Konstantinos | Chief Medical Officer | A | 75,000 | $0.0000 | $0.00 |
| Apr 1, 2026 | Xynos Konstantinos | Chief Medical Officer | A | 50,000 | $0.0000 | $0.00 |
| Apr 1, 2026 | Sarchi Christopher | Chief Commercial Officer | A | 75,000 | $0.0000 | $0.00 |
| Apr 1, 2026 | Sarchi Christopher | Chief Commercial Officer | A | 50,000 | $0.0000 | $0.00 |
| Apr 1, 2026 | BAKER BROS. ADVISORS LP | Director, 10% Owner | A | 44,500 | $0.0000 | $0.00 |
| Apr 1, 2026 | BAKER BROS. ADVISORS LP | Director, 10% Owner | A | 44,500 | $0.0000 | $0.00 |
| Apr 1, 2026 | Astley-Sparke Philip | Director | A | 75,000 | $0.0000 | $0.00 |
| Apr 1, 2026 | Astley-Sparke Philip | Director | A | 50,000 | $0.0000 | $0.00 |
| Feb 18, 2026 | Astley-Sparke Philip | Director | G | 25,000 | $0.0000 | $0.00 |
| Dec 19, 2025 | Schwendenman Andrew | Chief Accounting Officer | A | 10,000 | $0.0000 | $0.00 |
| Dec 19, 2025 | Sarchi Christopher | Chief Commercial Officer | A | 35,000 | $0.0000 | $0.00 |
| Dec 19, 2025 | Xynos Konstantinos | Chief Medical Officer | A | 60,000 | $0.0000 | $0.00 |
| Dec 19, 2025 | Hill Emily Luisa | Chief Financial Officer | A | 60,000 | $0.0000 | $0.00 |
| Dec 19, 2025 | Patel Sushil | Chief Executive Officer | A | 200,000 | $0.0000 | $0.00 |
| Dec 9, 2025 | Dhingra Kapil | Director | M | 3,169 | $0.0000 | $0.00 |
| Dec 9, 2025 | Dhingra Kapil | Director | S | 3,169 | $10.4000 | $32.96K |
| Dec 9, 2025 | Dhingra Kapil | Director | M | 3,169 | $1.7500 | $5.54K |
| Dec 2, 2025 | Patel Sushil | Chief Executive Officer | S | 10,000 | $11.1300 | $111.30K |
| Nov 17, 2025 | Xynos Konstantinos | Chief Medical Officer | S | 7,248 | $9.1000 | $65.96K |
| Nov 17, 2025 | Sarchi Christopher | Chief Commercial Officer | S | 5,208 | $9.1000 | $47.39K |
| Aug 15, 2025 | Hill Emily Luisa | Chief Financial Officer | S | 9,154 | $5.3700 | $49.16K |
| May 20, 2025 | Sarchi Christopher | Chief Commercial Officer | S | 3,749 | $8.0500 | $30.18K |