Insider Trades & Whales

Insider trades are parsed from SEC Form 4 filings (first-party). The ownership breakdown below is computed first-hand from SEC 13F-HR + Form 4 (institutions from 13F, insiders from Form 4). For the full filer list and quarter-over-quarter position changes, see the Institutional (13F) tab.

Ownership Breakdown

Insiders 14.52%Institutions 97.42%790 filers

Top Institutions

Form 4 Transactions

50 most recent

Date	Insider	Title	Code	Shares	Price	Value
Aug 19, 2026	CAGNONI PABLO J	President, Global Head of R&D	S	10,801	$125.5600	$1.36M
Aug 12, 2026	CAGNONI PABLO J	President, Global Head of R&D	S	10,803	$120.0400	$1.30M
Aug 5, 2026	Mayes Patrick A	EVP & Chief Scientific Officer	M	2,207	$0.0000	$0.00
Aug 5, 2026	Mayes Patrick A	EVP & Chief Scientific Officer	S	2,207	$123.9900	$273.64K
Aug 5, 2026	Mayes Patrick A	EVP & Chief Scientific Officer	M	2,207	$106.4700	$234.98K
Aug 5, 2026	CAGNONI PABLO J	President, Global Head of R&D	S	10,640	$122.6900	$1.31M
Aug 3, 2026	Mayes Patrick A	EVP & Chief Scientific Officer	M	6,055	$0.0000	$0.00
Aug 3, 2026	Mayes Patrick A	EVP & Chief Scientific Officer	S	6,055	$120.4300	$729.20K
Aug 3, 2026	Mayes Patrick A	EVP & Chief Scientific Officer	M	6,055	$105.4300	$638.38K
Jul 31, 2026	Mayes Patrick A	EVP & Chief Scientific Officer	M	326	$0.0000	$0.00
Jul 31, 2026	Mayes Patrick A	EVP & Chief Scientific Officer	M	85	$0.0000	$0.00
Jul 31, 2026	Mayes Patrick A	EVP & Chief Scientific Officer	M	2,293	$0.0000	$0.00
Jul 31, 2026	Mayes Patrick A	EVP & Chief Scientific Officer	M	1,642	$0.0000	$0.00
Jul 31, 2026	Mayes Patrick A	EVP & Chief Scientific Officer	M	2,623	$0.0000	$0.00
Jul 31, 2026	Mayes Patrick A	EVP & Chief Scientific Officer	M	3,023	$0.0000	$0.00
Jul 31, 2026	Mayes Patrick A	EVP & Chief Scientific Officer	M	1,643	$0.0000	$0.00
Jul 31, 2026	Mayes Patrick A	EVP & Chief Scientific Officer	M	2,864	$0.0000	$0.00
Jul 31, 2026	Mayes Patrick A	EVP & Chief Scientific Officer	M	2,623	$0.0000	$0.00
Jul 31, 2026	Mayes Patrick A	EVP & Chief Scientific Officer	M	9,459	$0.0000	$0.00
Jul 31, 2026	Mayes Patrick A	EVP & Chief Scientific Officer	M	2,072	$0.0000	$0.00
Jul 31, 2026	Mayes Patrick A	EVP & Chief Scientific Officer	M	3,148	$0.0000	$0.00
Jul 31, 2026	Mayes Patrick A	EVP & Chief Scientific Officer	M	2,709	$0.0000	$0.00
Jul 31, 2026	Mayes Patrick A	EVP & Chief Scientific Officer	M	2,284	$0.0000	$0.00
Jul 31, 2026	Mayes Patrick A	EVP & Chief Scientific Officer	M	2,918	$0.0000	$0.00
Jul 31, 2026	Mayes Patrick A	EVP & Chief Scientific Officer	S	2,293	$119.4100	$273.81K
Jul 31, 2026	Mayes Patrick A	EVP & Chief Scientific Officer	S	326	$121.6900	$39.67K
Jul 31, 2026	Mayes Patrick A	EVP & Chief Scientific Officer	S	85	$122.1900	$10.39K
Jul 31, 2026	Mayes Patrick A	EVP & Chief Scientific Officer	S	1,642	$119.3800	$196.02K
Jul 31, 2026	Mayes Patrick A	EVP & Chief Scientific Officer	S	1,643	$119.5100	$196.35K
Jul 31, 2026	Mayes Patrick A	EVP & Chief Scientific Officer	S	2,864	$119.4000	$341.96K
Jul 31, 2026	Mayes Patrick A	EVP & Chief Scientific Officer	S	4,695	$119.3900	$560.54K
Jul 31, 2026	Mayes Patrick A	EVP & Chief Scientific Officer	S	6,171	$119.4300	$737.00K
Jul 31, 2026	Mayes Patrick A	EVP & Chief Scientific Officer	S	2,187	$119.4700	$261.28K
Jul 31, 2026	Mayes Patrick A	EVP & Chief Scientific Officer	S	5,332	$119.4200	$636.75K
Jul 31, 2026	Mayes Patrick A	EVP & Chief Scientific Officer	S	14,661	$119.4600	$1.75M
Jul 31, 2026	Mayes Patrick A	EVP & Chief Scientific Officer	M	326	$105.4300	$34.37K
Jul 31, 2026	Mayes Patrick A	EVP & Chief Scientific Officer	M	85	$106.4700	$9.05K
Jul 31, 2026	Mayes Patrick A	EVP & Chief Scientific Officer	M	2,293	$90.5600	$207.65K
Jul 31, 2026	Mayes Patrick A	EVP & Chief Scientific Officer	M	1,642	$85.0100	$139.59K
Jul 31, 2026	Mayes Patrick A	EVP & Chief Scientific Officer	M	2,623	$83.5800	$219.23K
Jul 31, 2026	Mayes Patrick A	EVP & Chief Scientific Officer	M	3,023	$83.2000	$251.51K
Jul 31, 2026	Mayes Patrick A	EVP & Chief Scientific Officer	M	1,643	$80.5000	$132.26K
Jul 31, 2026	Mayes Patrick A	EVP & Chief Scientific Officer	M	2,864	$77.6700	$222.45K
Jul 31, 2026	Mayes Patrick A	EVP & Chief Scientific Officer	M	2,623	$74.7800	$196.15K
Jul 31, 2026	Mayes Patrick A	EVP & Chief Scientific Officer	M	9,459	$72.2700	$683.60K
Jul 31, 2026	Mayes Patrick A	EVP & Chief Scientific Officer	M	2,072	$71.9300	$149.04K
Jul 31, 2026	Mayes Patrick A	EVP & Chief Scientific Officer	M	3,148	$68.6200	$216.01K
Jul 31, 2026	Mayes Patrick A	EVP & Chief Scientific Officer	M	2,709	$61.7600	$167.31K
Jul 31, 2026	Mayes Patrick A	EVP & Chief Scientific Officer	M	2,284	$64.2500	$146.75K
Jul 31, 2026	Mayes Patrick A	EVP & Chief Scientific Officer	M	2,918	$61.1800	$178.52K

Insider Trades & Whales

Ownership Breakdown

Insiders 14.52%Institutions 97.42%790 filers

Top Institutions

Form 4 Transactions

50 most recent

Date	Insider	Title	Code	Shares	Price	Value
Aug 19, 2026	CAGNONI PABLO J	President, Global Head of R&D	S	10,801	$125.5600	$1.36M
Aug 12, 2026	CAGNONI PABLO J	President, Global Head of R&D	S	10,803	$120.0400	$1.30M
Aug 5, 2026	Mayes Patrick A	EVP & Chief Scientific Officer	M	2,207	$0.0000	$0.00
Aug 5, 2026	Mayes Patrick A	EVP & Chief Scientific Officer	S	2,207	$123.9900	$273.64K
Aug 5, 2026	Mayes Patrick A	EVP & Chief Scientific Officer	M	2,207	$106.4700	$234.98K
Aug 5, 2026	CAGNONI PABLO J	President, Global Head of R&D	S	10,640	$122.6900	$1.31M
Aug 3, 2026	Mayes Patrick A	EVP & Chief Scientific Officer	M	6,055	$0.0000	$0.00
Aug 3, 2026	Mayes Patrick A	EVP & Chief Scientific Officer	S	6,055	$120.4300	$729.20K
Aug 3, 2026	Mayes Patrick A	EVP & Chief Scientific Officer	M	6,055	$105.4300	$638.38K
Jul 31, 2026	Mayes Patrick A	EVP & Chief Scientific Officer	M	326	$0.0000	$0.00
Jul 31, 2026	Mayes Patrick A	EVP & Chief Scientific Officer	M	85	$0.0000	$0.00
Jul 31, 2026	Mayes Patrick A	EVP & Chief Scientific Officer	M	2,293	$0.0000	$0.00
Jul 31, 2026	Mayes Patrick A	EVP & Chief Scientific Officer	M	1,642	$0.0000	$0.00
Jul 31, 2026	Mayes Patrick A	EVP & Chief Scientific Officer	M	2,623	$0.0000	$0.00
Jul 31, 2026	Mayes Patrick A	EVP & Chief Scientific Officer	M	3,023	$0.0000	$0.00
Jul 31, 2026	Mayes Patrick A	EVP & Chief Scientific Officer	M	1,643	$0.0000	$0.00
Jul 31, 2026	Mayes Patrick A	EVP & Chief Scientific Officer	M	2,864	$0.0000	$0.00
Jul 31, 2026	Mayes Patrick A	EVP & Chief Scientific Officer	M	2,623	$0.0000	$0.00
Jul 31, 2026	Mayes Patrick A	EVP & Chief Scientific Officer	M	9,459	$0.0000	$0.00
Jul 31, 2026	Mayes Patrick A	EVP & Chief Scientific Officer	M	2,072	$0.0000	$0.00
Jul 31, 2026	Mayes Patrick A	EVP & Chief Scientific Officer	M	3,148	$0.0000	$0.00
Jul 31, 2026	Mayes Patrick A	EVP & Chief Scientific Officer	M	2,709	$0.0000	$0.00
Jul 31, 2026	Mayes Patrick A	EVP & Chief Scientific Officer	M	2,284	$0.0000	$0.00
Jul 31, 2026	Mayes Patrick A	EVP & Chief Scientific Officer	M	2,918	$0.0000	$0.00
Jul 31, 2026	Mayes Patrick A	EVP & Chief Scientific Officer	S	2,293	$119.4100	$273.81K
Jul 31, 2026	Mayes Patrick A	EVP & Chief Scientific Officer	S	326	$121.6900	$39.67K
Jul 31, 2026	Mayes Patrick A	EVP & Chief Scientific Officer	S	85	$122.1900	$10.39K
Jul 31, 2026	Mayes Patrick A	EVP & Chief Scientific Officer	S	1,642	$119.3800	$196.02K
Jul 31, 2026	Mayes Patrick A	EVP & Chief Scientific Officer	S	1,643	$119.5100	$196.35K
Jul 31, 2026	Mayes Patrick A	EVP & Chief Scientific Officer	S	2,864	$119.4000	$341.96K
Jul 31, 2026	Mayes Patrick A	EVP & Chief Scientific Officer	S	4,695	$119.3900	$560.54K
Jul 31, 2026	Mayes Patrick A	EVP & Chief Scientific Officer	S	6,171	$119.4300	$737.00K
Jul 31, 2026	Mayes Patrick A	EVP & Chief Scientific Officer	S	2,187	$119.4700	$261.28K
Jul 31, 2026	Mayes Patrick A	EVP & Chief Scientific Officer	S	5,332	$119.4200	$636.75K
Jul 31, 2026	Mayes Patrick A	EVP & Chief Scientific Officer	S	14,661	$119.4600	$1.75M
Jul 31, 2026	Mayes Patrick A	EVP & Chief Scientific Officer	M	326	$105.4300	$34.37K
Jul 31, 2026	Mayes Patrick A	EVP & Chief Scientific Officer	M	85	$106.4700	$9.05K
Jul 31, 2026	Mayes Patrick A	EVP & Chief Scientific Officer	M	2,293	$90.5600	$207.65K
Jul 31, 2026	Mayes Patrick A	EVP & Chief Scientific Officer	M	1,642	$85.0100	$139.59K
Jul 31, 2026	Mayes Patrick A	EVP & Chief Scientific Officer	M	2,623	$83.5800	$219.23K
Jul 31, 2026	Mayes Patrick A	EVP & Chief Scientific Officer	M	3,023	$83.2000	$251.51K
Jul 31, 2026	Mayes Patrick A	EVP & Chief Scientific Officer	M	1,643	$80.5000	$132.26K
Jul 31, 2026	Mayes Patrick A	EVP & Chief Scientific Officer	M	2,864	$77.6700	$222.45K
Jul 31, 2026	Mayes Patrick A	EVP & Chief Scientific Officer	M	2,623	$74.7800	$196.15K
Jul 31, 2026	Mayes Patrick A	EVP & Chief Scientific Officer	M	9,459	$72.2700	$683.60K
Jul 31, 2026	Mayes Patrick A	EVP & Chief Scientific Officer	M	2,072	$71.9300	$149.04K
Jul 31, 2026	Mayes Patrick A	EVP & Chief Scientific Officer	M	3,148	$68.6200	$216.01K
Jul 31, 2026	Mayes Patrick A	EVP & Chief Scientific Officer	M	2,709	$61.7600	$167.31K
Jul 31, 2026	Mayes Patrick A	EVP & Chief Scientific Officer	M	2,284	$64.2500	$146.75K
Jul 31, 2026	Mayes Patrick A	EVP & Chief Scientific Officer	M	2,918	$61.1800	$178.52K