| Date | Insider | Title | Code | Shares | Price | Value |
|---|---|---|---|---|---|---|
| Aug 18, 2026 | Lin Xichen | CHIEF SCIENTIFIC OFFICER | S | 1,200 | $55.0500 | $66.06K |
| Aug 18, 2026 | Lin Xichen | CHIEF SCIENTIFIC OFFICER | S | 1,557 | $54.1970 | $84.38K |
| Aug 18, 2026 | Lin Xichen | CHIEF SCIENTIFIC OFFICER | S | 9,060 | $53.1330 | $481.38K |
| Aug 18, 2026 | Lin Xichen | CHIEF SCIENTIFIC OFFICER | C | 11,817 | $0.0000 | $0.00 |
| Aug 18, 2026 | Lin Xichen | CHIEF SCIENTIFIC OFFICER | M | 11,817 | $0.0000 | $0.00 |
| Aug 18, 2026 | Lin Xichen | CHIEF SCIENTIFIC OFFICER | C | 11,817 | $0.0000 | $0.00 |
| Aug 18, 2026 | Lin Xichen | CHIEF SCIENTIFIC OFFICER | M | 11,817 | $0.3400 | $4.02K |
| Aug 6, 2026 | Berrios John Joseph | Chief Commercial Officer | A | 174,612 | $0.0000 | $0.00 |
| Aug 6, 2026 | Berrios John Joseph | Chief Commercial Officer | A | 140,766 | $0.0000 | $0.00 |
| Aug 4, 2026 | Lin Xichen | CHIEF SCIENTIFIC OFFICER | S | 2,517 | $50.0290 | $125.92K |
| Aug 4, 2026 | Lin Xichen | CHIEF SCIENTIFIC OFFICER | S | 9,300 | $49.2857 | $458.36K |
| Aug 4, 2026 | Lin Xichen | CHIEF SCIENTIFIC OFFICER | C | 11,817 | $0.0000 | $0.00 |
| Aug 4, 2026 | Lin Xichen | CHIEF SCIENTIFIC OFFICER | M | 11,817 | $0.0000 | $0.00 |
| Aug 4, 2026 | Lin Xichen | CHIEF SCIENTIFIC OFFICER | C | 11,817 | $0.0000 | $0.00 |
| Aug 4, 2026 | Lin Xichen | CHIEF SCIENTIFIC OFFICER | M | 11,817 | $0.3400 | $4.02K |
| Jul 22, 2026 | FMR LLC | 10% Owner, Other | S | 48,255 | $50.0700 | $2.42M |
| Jul 22, 2026 | FMR LLC | 10% Owner, Other | S | 4,101 | $50.0700 | $205.34K |
| Jul 14, 2026 | Lin Xichen | CHIEF SCIENTIFIC OFFICER | S | 4,800 | $51.7088 | $248.20K |
| Jul 14, 2026 | Lin Xichen | CHIEF SCIENTIFIC OFFICER | S | 18,834 | $50.7956 | $956.68K |
| Jul 14, 2026 | Lin Xichen | CHIEF SCIENTIFIC OFFICER | C | 23,634 | $0.0000 | $0.00 |
| Jul 14, 2026 | Lin Xichen | CHIEF SCIENTIFIC OFFICER | M | 23,634 | $0.0000 | $0.00 |
| Jul 14, 2026 | Lin Xichen | CHIEF SCIENTIFIC OFFICER | C | 23,634 | $0.0000 | $0.00 |
| Jul 14, 2026 | Lin Xichen | CHIEF SCIENTIFIC OFFICER | M | 23,634 | $0.3400 | $8.04K |
| Jun 25, 2026 | Lin Xichen | CHIEF SCIENTIFIC OFFICER | S | 23,634 | $49.0792 | $1.16M |
| Jun 25, 2026 | Lin Xichen | CHIEF SCIENTIFIC OFFICER | C | 23,634 | $0.0000 | $0.00 |
| Jun 25, 2026 | Lin Xichen | CHIEF SCIENTIFIC OFFICER | M | 23,634 | $0.0000 | $0.00 |
| Jun 25, 2026 | Lin Xichen | CHIEF SCIENTIFIC OFFICER | C | 23,634 | $0.0000 | $0.00 |
| Jun 25, 2026 | Lin Xichen | CHIEF SCIENTIFIC OFFICER | M | 23,634 | $0.3400 | $8.04K |
| Jun 17, 2026 | WELCH DANIEL G | Director | A | 39,453 | $0.0000 | $0.00 |
| Jun 17, 2026 | TETLOW SHARON | Director | A | 39,453 | $0.0000 | $0.00 |
| Jun 17, 2026 | DOBMEIER ERIC | Director | A | 39,453 | $0.0000 | $0.00 |
| Jun 17, 2026 | Waldstreicher Joanne | Director | A | 39,453 | $0.0000 | $0.00 |
| Jun 17, 2026 | LOVE TED W | Director | A | 39,453 | $0.0000 | $0.00 |
| Jun 17, 2026 | Russell Angus C. | Director | A | 39,453 | $0.0000 | $0.00 |
| Apr 15, 2026 | Lang Matthew | COO & GC | A | 223,776 | $0.0000 | $0.00 |
| Apr 15, 2026 | Lang Matthew | COO & GC | A | 184,614 | $0.0000 | $0.00 |
| Apr 14, 2026 | FMR LLC | 10% Owner, Other | S | 16,085 | $55.0700 | $885.80K |
| Apr 14, 2026 | FMR LLC | 10% Owner, Other | S | 1,367 | $55.0700 | $75.28K |
| Mar 19, 2026 | Ma Yingli | CHIEF TECHNOLOGY OFFICER | A | 40,278 | $0.0000 | $0.00 |
| Mar 19, 2026 | Ma Yingli | CHIEF TECHNOLOGY OFFICER | A | 32,526 | $0.0000 | $0.00 |
| Mar 19, 2026 | Stevens Raymond C | CHIEF EXECUTIVE OFFICER | A | 322,230 | $0.0000 | $0.00 |
| Mar 19, 2026 | Stevens Raymond C | CHIEF EXECUTIVE OFFICER | A | 260,217 | $0.0000 | $0.00 |
| Mar 19, 2026 | Lin Xichen | CHIEF SCIENTIFIC OFFICER | A | 53,703 | $0.0000 | $0.00 |
| Mar 19, 2026 | Lin Xichen | CHIEF SCIENTIFIC OFFICER | A | 43,368 | $0.0000 | $0.00 |
| Mar 19, 2026 | Coll Crespo Blas | CHIEF MEDICAL OFFICER | A | 93,984 | $0.0000 | $0.00 |
| Mar 19, 2026 | Coll Crespo Blas | CHIEF MEDICAL OFFICER | A | 75,897 | $0.0000 | $0.00 |
| Mar 19, 2026 | Yoon Jun | CHIEF FINANCIAL OFFICER | A | 128,892 | $0.0000 | $0.00 |
| Mar 19, 2026 | Yoon Jun | CHIEF FINANCIAL OFFICER | A | 104,085 | $0.0000 | $0.00 |
| Mar 19, 2026 | Hall Ashley | Chief Development Officer | A | 59,073 | $0.0000 | $0.00 |
| Mar 19, 2026 | Hall Ashley | Chief Development Officer | A | 47,706 | $0.0000 | $0.00 |