| Apr 15, 2026 (view filing) | Apr 15 | Same day | Dube Eric MCHIEF EXECUTIVE OFFICER | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −64.0K | $41.09 | −$2.63M | −12.9%432.9K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Apr 15, 2026 (view filing) | Apr 14 | 1 day | Heerma PeterCHIEF COMMERCIAL OFFICER | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −7.21K | $41.93 | −$302.5K | −4.9%138.6K after | |
| Apr 15, 2026 (view filing) | Apr 14-15 | 1 day | Inrig JulaCHIEF MEDICAL OFFICER | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −8.23K | $42.01 | −$345.9K | −6.9%111.5K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Apr 15, 2026 (view filing) | Apr 13-15 | 2 days | Cline Christopher R.CHIEF FINANCIAL OFFICER | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −8.33K | $41.91 | −$349.0K | −6.6%116.9K after | 4 lotsThis row combines 4 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Apr 16, 2026 (view filing) | Apr 14 | 2 days | Lyons Gary ADirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −8.00K | $41.07 | −$328.6K | −12.2%57.5K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Apr 16, 2026 (view filing) | Apr 14 | 2 days | Baynes Roy D.Director | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −32.8K | $41.29 | −$1.35M | −46.6%37.5K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Apr 16, 2026 (view filing) | Apr 14 | 2 days | Calvin SandraSVP, CHIEF ACCOUNTING OFFICER | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −22.0K | $41.07 | −$902.6K | −34.2%42.4K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Apr 23, 2026 (view filing) | Apr 22 | 1 day | Rote William E.Chief Research Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −9.10K | $39.09 | −$355.7K | −7.4%114.0K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| May 4, 2026 (view filing) | May 1 | 3 days | Baynes Roy D.Director | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −9.75K | $44.22 | −$431.1K | −20.6%37.5K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| May 6, 2026 (view filing) | May 4-6 | 2 days | Reed Elizabeth EChief Legal Officer and GC | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −24.3K | $45.06 | −$1.09M | −18.7%105.2K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| May 6, 2026 (view filing) | May 4 | 2 days | Meckler Jeffrey ADirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −8.00K | $45.00 | −$360.0K | −8.4%87.5K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| May 6, 2026 (view filing) | May 5 | 1 day | Baynes Roy D.Director | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −4.50K | $46.65 | −$209.9K | −10.7%37.5K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| May 6, 2026 (view filing) | May 6 | Same day | Rote William E.Chief Research Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −2.76K | $43.95 | −$121.4K | −2.3%115.5K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| May 6, 2026 (view filing) | May 6 | Same day | Dube Eric MCHIEF EXECUTIVE OFFICER | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −22.5K | $43.95 | −$988.9K | −4.9%432.9K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| May 6, 2026 (view filing) | May 5 | 1 day | Heerma PeterCHIEF COMMERCIAL OFFICER | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −2.17K | $46.65 | −$101.4K | −1.5%140.7K after | |
| May 6, 2026 (view filing) | May 4-6 | 2 days | Inrig JulaCHIEF MEDICAL OFFICER | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −22.5K | $45.15 | −$1.02M | −16.6%113.2K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| May 6, 2026 (view filing) | May 5-6 | 1 day | Cline Christopher R.CHIEF FINANCIAL OFFICER | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −2.49K | $46.31 | −$115.4K | −2.1%118.7K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| May 19, 2026 (view filing) | May 15 | 4 days | Coughlin TimothyDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −3.25K | $43.49 | −$141.3K | −5.9%52.3K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jun 16, 2026 (view filing) | Jun 12 | 4 days | Coughlin TimothyDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −10.0K | $50.07 | −$500.7K | −15.1%56.3K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jun 16, 2026 (view filing) | Jun 12 | 4 days | Baynes Roy D.Director | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −4.50K | $50.00 | −$225.0K | −9.8%41.5K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Aug 19, 2026 (view filing)4:05 PM ET | Aug 17-18 | 2 days | Lyons Gary ADirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −10.0K | $63.28 | −$632.8K | −14.0%61.5K after | 5 lotsThis row combines 5 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Sep 3, 2026 (view filing)4:05 PM ET | Sep 2 | 1 day | Cline Christopher R.CHIEF FINANCIAL OFFICER | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −642 | $66.37 | −$42.6K | −0.5%118.0K after | |
| Sep 11, 2026 (view filing)4:05 PM ET | Sep 10 | 1 day | Meckler Jeffrey ADirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −20.0K | $67.31 | −$1.35M | −17.9%91.5K after | 4 lotsThis row combines 4 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Sep 17, 2026 (view filing)9:29 PM ET | Sep 15 | 2 days | Calvin SandraSVP, CHIEF ACCOUNTING OFFICER | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −5.38K | $62.33 | −$335.0K | −11.3%42.4K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Sep 17, 2026 (view filing)9:30 PM ET | Sep 15 | 2 days | Cline Christopher R.CHIEF FINANCIAL OFFICER | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −50.5K | $62.34 | −$3.15M | −36.6%87.5K after | 4 lotsThis row combines 4 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Sep 17, 2026 (view filing)9:31 PM ET | Sep 15-17 | 2 days | Dube Eric MCHIEF EXECUTIVE OFFICER | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −400.0K | $63.48 | −$25.4M | −48.0%432.9K after | 8 lotsThis row combines 8 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Sep 17, 2026 (view filing)9:32 PM ET | Sep 15 | 2 days | Reed Elizabeth EChief Legal Officer and GC | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −37.5K | $62.34 | −$2.34M | −26.2%105.4K after | 4 lotsThis row combines 4 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Sep 17, 2026 (view filing)9:33 PM ET | Sep 15 | 2 days | Inrig JulaEVP, Head of R&D & CMO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −44.7K | $62.34 | −$2.79M | −30.8%100.5K after | 4 lotsThis row combines 4 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Sep 17, 2026 (view filing)9:35 PM ET | Sep 15-17 | 2 days | Heerma PeterEVP, CHIEF COMMERCIAL OFFICER | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −283.2K | $63.06 | −$17.9M | −70.8%117.1K after | 7 lotsThis row combines 7 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Sep 17, 2026 (view filing)9:35 PM ET | Sep 15-16 | 2 days | Rote William E.Chief Research Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −209.0K | $62.83 | −$13.1M | −68.0%98.2K after | 6 lotsThis row combines 6 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
