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Repligen Corp

RGEN
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0000730272

In the last 90 days, Repligen Corp insiders filed 0 open-market purchases and 5 sales; 481 institutions reported holding it in 13F filings for Q2 2026, worth $9.00B in total; 3 superinvestors hold it, including Maverick Capital and Duquesne Family Office.

13F holders, Q4 2025

Institutional positions in Repligen Corp as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
475
+34 vs. Q3 2025
Shares held
62.5M
+2.82M (+4.7%) vs. Q3 2025
Total value
$10.2B
+$2.26B (+28.3%) vs. Q3 2025
New holders
96
150 more added
Sold out
62
145 more reduced

12 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting RGEN on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 475 institutions
Q1 2021: 459 institutionsQ2 2021: 430 institutionsQ3 2021: 481 institutionsQ4 2021: 508 institutionsQ1 2022: 450 institutionsQ2 2022: 406 institutionsQ3 2022: 434 institutionsQ4 2022: 443 institutionsQ1 2023: 448 institutionsQ2 2023: 448 institutionsQ3 2023: 440 institutionsQ4 2023: 467 institutionsQ1 2024: 487 institutionsQ2 2024: 455 institutionsQ3 2024: 445 institutionsQ4 2024: 431 institutionsQ1 2025: 441 institutionsQ2 2025: 446 institutionsQ3 2025: 453 institutionsQ4 2025: 475 institutionsQ1 2026: 445 institutionsQ2 2026: 481 institutions
Value heldQ4 2025: $10.2B
Q1 2021: $8.88BQ2 2021: $9.28BQ3 2021: $13.6BQ4 2021: $12.5BQ1 2022: $9.15BQ2 2022: $8.17BQ3 2022: $9.56BQ4 2022: $9.06BQ1 2023: $9.06BQ2 2023: $7.74BQ3 2023: $9.08BQ4 2023: $10.4BQ1 2024: $10.3BQ2 2024: $7.06BQ3 2024: $8.25BQ4 2024: $8.09BQ1 2025: $7.33BQ2 2025: $7.22BQ3 2025: $8.00BQ4 2025: $10.2BQ1 2026: $7.75BQ2 2026: $9.00B
Institutions holding RGEN and their total value by quarter
QuarterHoldersValue
Q2 2026481$9.00B
Q1 2026445$7.75B
Q4 2025475$10.2B
Q3 2025453$8.00B
Q2 2025446$7.22B
Q1 2025441$7.33B
Q4 2024431$8.09B
Q3 2024445$8.25B
Q2 2024455$7.06B
Q1 2024487$10.3B
Q4 2023467$10.4B
Q3 2023440$9.08B
Q2 2023448$7.74B
Q1 2023448$9.06B
Q4 2022443$9.06B
Q3 2022434$9.56B
Q2 2022406$8.17B
Q1 2022450$9.15B
Q4 2021508$12.5B
Q3 2021481$13.6B
Q2 2021430$9.28B
Q1 2021459$8.88B

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Repligen Corp; share changes are against Q3 2025.

Institutions holding RGEN in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Elyxium Wealth, LLC45$7.37K0.00%+45New
Elequin Capital LP43$7.05K0.00%+43New
Clal Insurance Enterprises Holdings Ltd40$7.00K0.00%−42−51.2%Reduced
Smithfield Trust Co35$6.00K0.00%00.0%Unchanged
McIlrath & Eck, LLC35$5.74K0.00%00.0%Unchanged
J.Safra Asset Management Corp32$5.24K0.00%+27+540.0%Added
Flagship Harbor Advisors, LLC31$5.08K0.00%+31New
Pinnacle Wealth Planning Services, Inc.31$5.08K0.00%+31New
Bayban31$5.08K0.00%+31New
HHM Wealth Advisors, LLC30$4.92K0.00%00.0%Unchanged
Central Trust Co30$4.92K0.00%+6+25.0%Added
CBIZ Investment Advisory Services, LLC30$4.92K0.00%+30New
TD Waterhouse Canada Inc.30$4.92K0.00%+30New
1015 Capital Partners, LLC29$4.75K0.00%+29New
Meramec Financial Planners, LLC33$4.69K0.00%+33New
Atlantic Union Bankshares Corp28$4.59K0.00%+28New
Massmutual Trust Co FSB27$4.42K0.00%+12+80.0%Added
EverSource Wealth Advisors, LLC26$4.26K0.00%+14+116.7%Added
GHP Investment Advisors, Inc.25$4.10K0.00%00.0%Unchanged
Evolution Wealth Management Inc.25$4.10K0.00%00.0%Unchanged
Raelipskie Partnership25$4.10K0.00%00.0%Unchanged
Financial Network Wealth Advisors LLC25$4.10K0.00%+15+150.0%Added
Crewe Advisors LLC22$3.60K0.00%+22New
High Note Wealth, LLC22$3.60K0.00%+22New
Bellevue Asset Management, LLC22$3.60K0.00%+11+100.0%Added
Retirement Wealth Solutions LLC21$3.44K0.00%+2+10.5%Added
Ronald Blue Trust, Inc.20$3.28K0.00%00.0%Unchanged
Fourth Dimension Wealth, LLC20$3.28K0.00%00.0%Unchanged
CoreCap Advisors, LLC20$3.28K0.00%+20New
Prestige Wealth Management Group LLC19$3.12K0.00%00.0%Unchanged
Walleye Trading LLC18$2.95K0.00%−943−98.1%Reduced
Aventura Private Wealth, LLC18$2.95K0.00%−22−55.0%Reduced
Grove Bank & Trust18$2.95K0.00%+18New
Spire Wealth Management16$2.62K0.00%00.0%Unchanged
Fortitude Family Office, LLC16$2.62K0.00%+4+33.3%Added
MAI Capital Management15$2.46K0.00%−22−59.5%Reduced
Atlantic Edge Private Wealth Management, LLC15$2.46K0.00%00.0%Unchanged
Signature Equity Partners, LLC13$2.13K0.00%+13New
Assetmark, Inc12$1.97K0.00%00.0%Unchanged
Ancora Advisors, LLC12$1.97K0.00%00.0%Unchanged
Front Row Advisors LLC12$1.97K0.00%00.0%Unchanged
Harbour Investments, Inc.12$1.97K0.00%+1+9.1%Added
S&T Bank12$1.97K0.00%+8+200.0%Added
Keating Financial Advisory Services, Inc.12$1.97K0.00%+12New
JFS Wealth Advisors, LLC11$1.80K0.00%+7+175.0%Added
McGuire Capital Advisors Inc11$1.80K0.00%+11New
Salomon & Ludwin, LLC10$1.69K0.00%00.0%Unchanged
Montag A & Associates Inc10$1.64K0.00%−1−9.1%Reduced
Transamerica Financial Advisors, Inc.10$1.64K0.00%00.0%Unchanged
TD Private Client Wealth LLC10$1.64K0.00%00.0%Unchanged
Rossby Financial, LCC10$1.64K0.00%+2+25.0%Added
First Horizon Corp10$1.64K0.00%+8+400.0%Added
Cornerstone Financial Management LLC10$1.64K0.00%+10New
Essential Partners LLC7$1.15K0.00%00.0%Unchanged
DiNuzzo Private Wealth, Inc.6$9840.00%+6New
Cromwell Holdings LLC6$9830.00%00.0%Unchanged
Quattro Advisors LLC5$8190.00%+5New
South State Corp.4$6560.00%00.0%Unchanged
Advocate Investing Services LLC4$6550.00%+4New
Bell Investment Advisors, Inc3$4920.00%00.0%Unchanged
Raffa Wealth Management, LLC3$4920.00%00.0%Unchanged
Strategic Advocates LLC2$3330.00%00.0%Unchanged
MV Capital Management, Inc.2$3280.00%00.0%Unchanged
SJS Investment Consulting Inc.2$3280.00%00.0%Unchanged
ZRC Wealth Management, LLC2$3280.00%00.0%Unchanged
HFM Investment Advisors, LLC2$3280.00%00.0%Unchanged
Rialto Wealth Management, LLC2$3280.00%+1+100.0%Added
DV Trading LLC2$3280.00%+2New
Bay Harbor Wealth Management, LLC2$3270.00%+1+100.0%Added
Manchester Capital Management LLC1$1640.00%00.0%Unchanged
Quaker Wealth Management, LLC1$1640.00%00.0%Unchanged
Private Wealth Asset Management, LLC1$1640.00%00.0%Unchanged
TFC Financial Management1$1640.00%+1New
Dunhill Financial, LLC1$1560.00%+1New
Capital Advisors, Ltd. LLC1$00.00%00.0%Unchanged
PointState Capital LP0$00.00%−409,503−100.0%Sold out
D. E. Shaw & Co., Inc.0$00.00%−249,930−100.0%Sold out
Squarepoint Ops LLC0$00.00%−175,248−100.0%Sold out
Voloridge Investment Management, LLC0$00.00%−141,042−100.0%Sold out
Tudor Investment Corp Et Al0$00.00%−129,522−100.0%Sold out
Alyeska Investment Group, L.P.0$00.00%−123,000−100.0%Sold out
Renaissance Technologies LLC0$00.00%−109,404−100.0%Sold out
Eversept Partners, LP0$00.00%−105,087−100.0%Sold out
Macquarie Group Ltd0$00.00%−90,308−100.0%Sold out
Eventide Asset Management, LLC0$00.00%−77,711−100.0%Sold out
Man Group plc0$00.00%−76,187−100.0%Sold out
ExodusPoint Capital Management, LP0$00.00%−64,531−100.0%Sold out
First Light Asset Management, LLC0$00.00%−41,427−100.0%Sold out
Assenagon Asset Management S.A.0$00.00%−40,569−100.0%Sold out
Caption Management, LLC0$00.00%−28,894−100.0%Sold out
Jump Financial, LLC0$00.00%−23,086−100.0%Sold out
CenterBook Partners LP0$00.00%−17,672−100.0%Sold out
Schonfeld Strategic Advisors LLC0$00.00%−16,331−100.0%Sold out
Verition Fund Management LLC0$00.00%−13,186−100.0%Sold out
Lighthouse Investment Partners, LLC0$00.00%−13,000−100.0%Sold out
Parallax Volatility Advisers, L.P.0$00.00%−11,314−100.0%Sold out
Sandler Capital Management0$00.00%−11,304−100.0%Sold out
Edgestream Partners, L.P.0$00.00%−10,398−100.0%Sold out
Algert Global LLC0$00.00%−9,530−100.0%Sold out
Gsa Capital Partners LLP0$00.00%−7,449−100.0%Sold out