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Repligen Corp

RGEN
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0000730272

In the last 90 days, Repligen Corp insiders filed 0 open-market purchases and 5 sales; 481 institutions reported holding it in 13F filings for Q2 2026, worth $9.00B in total; 3 superinvestors hold it, including Maverick Capital and Duquesne Family Office.

13F holders, Q4 2025

Institutional positions in Repligen Corp as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
475
+34 vs. Q3 2025
Shares held
62.5M
+2.82M (+4.7%) vs. Q3 2025
Total value
$10.2B
+$2.26B (+28.3%) vs. Q3 2025
New holders
96
150 more added
Sold out
62
145 more reduced

12 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting RGEN on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 475 institutions
Q1 2021: 459 institutionsQ2 2021: 430 institutionsQ3 2021: 481 institutionsQ4 2021: 508 institutionsQ1 2022: 450 institutionsQ2 2022: 406 institutionsQ3 2022: 434 institutionsQ4 2022: 443 institutionsQ1 2023: 448 institutionsQ2 2023: 448 institutionsQ3 2023: 440 institutionsQ4 2023: 467 institutionsQ1 2024: 487 institutionsQ2 2024: 455 institutionsQ3 2024: 445 institutionsQ4 2024: 431 institutionsQ1 2025: 441 institutionsQ2 2025: 446 institutionsQ3 2025: 453 institutionsQ4 2025: 475 institutionsQ1 2026: 445 institutionsQ2 2026: 481 institutions
Value heldQ4 2025: $10.2B
Q1 2021: $8.88BQ2 2021: $9.28BQ3 2021: $13.6BQ4 2021: $12.5BQ1 2022: $9.15BQ2 2022: $8.17BQ3 2022: $9.56BQ4 2022: $9.06BQ1 2023: $9.06BQ2 2023: $7.74BQ3 2023: $9.08BQ4 2023: $10.4BQ1 2024: $10.3BQ2 2024: $7.06BQ3 2024: $8.25BQ4 2024: $8.09BQ1 2025: $7.33BQ2 2025: $7.22BQ3 2025: $8.00BQ4 2025: $10.2BQ1 2026: $7.75BQ2 2026: $9.00B
Institutions holding RGEN and their total value by quarter
QuarterHoldersValue
Q2 2026481$9.00B
Q1 2026445$7.75B
Q4 2025475$10.2B
Q3 2025453$8.00B
Q2 2025446$7.22B
Q1 2025441$7.33B
Q4 2024431$8.09B
Q3 2024445$8.25B
Q2 2024455$7.06B
Q1 2024487$10.3B
Q4 2023467$10.4B
Q3 2023440$9.08B
Q2 2023448$7.74B
Q1 2023448$9.06B
Q4 2022443$9.06B
Q3 2022434$9.56B
Q2 2022406$8.17B
Q1 2022450$9.15B
Q4 2021508$12.5B
Q3 2021481$13.6B
Q2 2021430$9.28B
Q1 2021459$8.88B

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Repligen Corp; share changes are against Q3 2025.

Institutions holding RGEN in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Royal Bank of Canada143,326$23.5M0.00%−96,501−40.2%Reduced
Royce & Associates LP146,973$24.1M0.24%−1,685−1.1%Reduced
Segall Bryant & Hamill, LLC146,980$24.1M0.33%+7,602+5.5%Added
Comerica Bank149,083$24.4M0.10%+36,049+31.9%Added
Loomis Sayles & Co L P149,777$24.5M0.03%−18,274−10.9%Reduced
Moore Capital Management, LP150,000$24.6M0.50%+5,000+3.4%Added
Barclays PLC159,152$26.1M0.01%−97,690−38.0%Reduced
Ranger Investment Management, L.P.162,450$26.6M1.83%−515−0.3%Reduced
UBS Asset Management Americas Inc164,354$26.9M0.01%−213−0.1%Reduced
Raymond James Financial Inc168,874$27.9M0.01%+18,732+12.5%Added
New York State Common Retirement Fund171,010$28.0M0.04%−76,496−30.9%Reduced
SEI Investments Co181,988$29.8M0.03%−33,048−15.4%Reduced
Primecap Management Co186,668$30.6M0.02%−200−0.1%Reduced
Nuveen, LLC192,688$31.6M0.01%+55,352+40.3%Added
Artisan Partners Limited Partnership193,697$31.7M0.05%−19,044−9.0%Reduced
Principal Financial Group Inc198,204$32.5M0.02%+80,778+68.8%Added
NZS Capital, LLC198,803$32.6M1.00%+2,026+1.0%Added
Nomura Asset Management International Inc.204,863$33.6M0.05%+204,863New
Baird Financial Group, Inc.205,605$33.7M0.05%−11,608−5.3%Reduced
Palisade Capital Management LLC232,196$38.0M1.13%−29,602−11.3%Reduced
12 West Capital Management LP241,233$39.5M4.71%00.0%Unchanged
JPMorgan Chase & Co248,937$40.8M0.00%−24,511−9.0%Reduced
American Century Companies Inc250,273$41.0M0.02%−2,520−1.0%Reduced
Brown Capital Management LLC273,972$44.9M3.68%−394,886−59.0%Reduced
First Trust Advisors LP282,776$46.3M0.03%+16,486+6.2%Added
Goldman Sachs Group Inc295,271$48.4M0.01%+174,771+145.0%Added
Blue Whale Capital LLP308,467$50.5M2.59%+65,366+26.9%Added
Allspring Global Investments Holdings, LLC311,175$51.1M0.08%+7,430+2.4%Added
Riverbridge Partners LLC313,365$51.3M0.96%−30,070−8.8%Reduced
Perceptive Advisors LLC315,541$51.7M0.95%+45,113+16.7%Added
Iron Triangle Partners LP320,474$52.5M6.00%+50,474+18.7%Added
BNP PARIBAS ASSET MANAGEMENT Holding S.A.323,821$53.1M0.06%+40,369+14.2%Added
American Capital Management Inc335,115$54.9M2.42%−1,747−0.5%Reduced
UBS Group AG348,388$57.1M0.01%−108,541−23.8%Reduced
Bank of America Corp397,229$65.1M0.00%+7,848+2.0%Added
Artemis Investment Management LLP410,369$67.2M0.81%+63,583+18.3%Added
Thrivent Financial for Lutherans411,706$67.5M0.12%−47,114−10.3%Reduced
Impax Asset Management Group plc413,384$67.7M0.42%−289,853−41.2%Reduced
Walleye Capital LLC417,110$68.3M0.39%+231,353+124.5%Added
Charles Schwab Investment Management Inc430,704$70.6M0.01%+8,616+2.0%Added
TimesSquare Capital Management, LLC435,687$71.4M1.08%+73,558+20.3%Added
Schroder Investment Management Group443,934$72.7M0.06%−16,675−3.6%Reduced
Northern Trust Corp446,148$73.1M0.01%−17,978−3.9%Reduced
Norges Bank462,094$75.7M0.01%+462,094New
Ameriprise Financial Inc494,225$81.0M0.02%−15,386−3.0%Reduced
DF Dent & Co Inc495,550$81.2M1.17%−39,169−7.3%Reduced
Marshall Wace, LLP516,336$84.6M0.08%+335,273+185.2%Added
Voya Investment Management LLC521,158$85.4M0.08%+218,524+72.2%Added
Bamco Inc544,779$89.3M0.24%+163,101+42.7%Added
Geneva Capital Management LLC562,975$92.2M1.73%−33,793−5.7%Reduced
Morgan Stanley570,977$93.6M0.01%+86,002+17.7%Added
T. Rowe Price Investment Management, Inc.646,122$105.9M0.07%+74,044+12.9%Added
Millennium Management LLC650,546$106.6M0.08%−166,510−20.4%Reduced
Stephens Investment Management Group LLC657,111$107.7M1.40%+58,755+9.8%Added
Congress Asset Management Co746,306$122.3M0.86%+527,714+241.4%Added
Dimensional Fund Advisors LP804,410$131.8M0.03%+4,900+0.6%Added
Fred Alger Management, LLC911,527$149.4M0.59%+553,105+154.3%Added
Holocene Advisors, LP961,040$157.5M0.33%−416,064−30.2%Reduced
Alliancebernstein L.P.994,869$163.0M0.05%−109,302−9.9%Reduced
Champlain Investment Partners, LLC1,003,951$164.5M1.67%−335,295−25.0%Reduced
Point72 Asset Management, L.P.1,006,310$164.9M0.26%−434,411−30.2%Reduced
Geode Capital Management, LLC1,029,817$168.8M0.01%−2,622−0.3%Reduced
Conestoga Capital Advisors, LLC1,057,975$173.4M2.92%+101,062+10.6%Added
RTW Investments, LP1,064,000$174.3M1.75%+1,064,000New
Franklin Resources Inc1,101,447$180.5M0.04%+677,146+159.6%Added
Massachusetts Financial Services Co1,215,527$199.2M0.06%+1,215,527New
Invesco Ltd.1,256,439$205.9M0.02%+383,399+43.9%Added
Bank of New York Mellon Corp1,344,706$220.3M0.04%+28,870+2.2%Added
Citadel Advisors LLC1,394,252$228.5M0.16%−290,468−17.2%Reduced
State Street Corp1,719,093$281.7M0.01%−82,443−4.6%Reduced
United Capital Financial Advisers, LLC2,770,862$454.0M2.74%+14,919+0.5%Added
FMR LLC2,867,846$469.9M0.02%+176,634+6.6%Added
Price T Rowe Associates Inc4,599,061$753.6M0.08%+1,091,683+31.1%Added
Vanguard Group Inc4,993,945$818.3M0.01%−50,246−1.0%Reduced
BlackRock, Inc.6,619,271$1.08B0.02%+479,541+7.8%Added
PointState Capital LP0$00.00%−409,503−100.0%Sold out
D. E. Shaw & Co., Inc.0$00.00%−249,930−100.0%Sold out
Squarepoint Ops LLC0$00.00%−175,248−100.0%Sold out
Voloridge Investment Management, LLC0$00.00%−141,042−100.0%Sold out
Tudor Investment Corp Et Al0$00.00%−129,522−100.0%Sold out
Alyeska Investment Group, L.P.0$00.00%−123,000−100.0%Sold out
Renaissance Technologies LLC0$00.00%−109,404−100.0%Sold out
Eversept Partners, LP0$00.00%−105,087−100.0%Sold out
Macquarie Group Ltd0$00.00%−90,308−100.0%Sold out
Eventide Asset Management, LLC0$00.00%−77,711−100.0%Sold out
Man Group plc0$00.00%−76,187−100.0%Sold out
ExodusPoint Capital Management, LP0$00.00%−64,531−100.0%Sold out
First Light Asset Management, LLC0$00.00%−41,427−100.0%Sold out
Assenagon Asset Management S.A.0$00.00%−40,569−100.0%Sold out
Caption Management, LLC0$00.00%−28,894−100.0%Sold out
Jump Financial, LLC0$00.00%−23,086−100.0%Sold out
CenterBook Partners LP0$00.00%−17,672−100.0%Sold out
Schonfeld Strategic Advisors LLC0$00.00%−16,331−100.0%Sold out
Verition Fund Management LLC0$00.00%−13,186−100.0%Sold out
Lighthouse Investment Partners, LLC0$00.00%−13,000−100.0%Sold out
Parallax Volatility Advisers, L.P.0$00.00%−11,314−100.0%Sold out
Sandler Capital Management0$00.00%−11,304−100.0%Sold out
Edgestream Partners, L.P.0$00.00%−10,398−100.0%Sold out
Algert Global LLC0$00.00%−9,530−100.0%Sold out
Gsa Capital Partners LLP0$00.00%−7,449−100.0%Sold out