| Oct 14, 2025 (view filing) | Oct 13 | 1 day | Albers Jeffrey W.Director | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −5.00K | $59.19 | −$295.9K | −100.0%0 after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Sep 17, 2025 (view filing) | Sep 17 | Same day | Jacobs Bruce N.Chief Financial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −79.2K | $50.00 | −$3.96M | −25.8%227.4K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Sep 16, 2025 (view filing) | Sep 16 | Same day | Mainolfi NelloChief Executive Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −30.0K | $49.00 | −$1.47M | −4.3%660.5K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jul 1, 2025 (view filing)6:41 PM ET | Jun 30 | 1 day | Biotechnology Value Fund L P and 9 othersDirector, Other: See Remarks and Footnotes | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Common Stock, $0.0001 par value | +317.2K | $44.00 | +$14.0M | +875.1%353.4K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average. |
| Jun 30, 2025 (view filing)8:15 PM ET | Jun 30 | Same day | Baker Julian and 5 othersDirector | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in. | +655.5K | $44.00 | +$28.8M | +12.0%6.12M after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Jun 30, 2025 (view filing)8:15 PM ET | Jun 30 | Same day | Baker Julian and 5 othersDirector | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in. | +655.5K | $44.00 | +$28.8M | –10.2M after | DerivativeA trade in a derivative security (option, warrant, restricted stock unit and so on). The value is the derivative's own price times the quantity.2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Jun 11, 2025 (view filing) | Jun 11 | Same day | Ridloff ElenaDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −4.50K | $50.00 | −$225.0K | −100.0%0 after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jun 3, 2025 (view filing) | Jun 3 | Same day | Esposito PamelaDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −5.00K | $49.04 | −$245.2K | −100.0%0 after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jun 3, 2025 (view filing) | Jun 3 | Same day | Ridloff ElenaDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −12.0K | $46.10 | −$553.2K | −100.0%0 after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jun 3, 2025 (view filing) | Jun 3 | Same day | Mainolfi NelloChief Executive Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −30.0K | $49.00 | −$1.47M | −4.3%660.5K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jun 3, 2025 (view filing) | Jun 3 | Same day | Albers Jeffrey W.Director | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −6.35K | $49.00 | −$311.1K | −100.0%0 after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| May 23, 2025 (view filing) | May 23 | Same day | Chadwick Jeremy GChief Operating Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −2.58K | $29.30 | −$75.4K | −3.7%66.4K after | |
| Mar 3, 2025 (view filing) | Mar 3 | Same day | Chiniara EllenChief Legal Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −2.24K | $30.45 | −$68.2K | −2.7%80.1K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Mar 3, 2025 (view filing) | Mar 3 | Same day | Chadwick Jeremy GChief Operating Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.38K | $30.45 | −$42.1K | −2.0%67.8K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Mar 3, 2025 (view filing) | Mar 3 | Same day | Jacobs Bruce N.Chief Financial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −7.04K | $30.45 | −$214.2K | −3.4%201.9K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Mar 3, 2025 (view filing) | Mar 3 | Same day | Gollob JaredChief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −5.74K | $30.45 | −$174.8K | −4.6%120.0K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Jan 6, 2025 (view filing) | Jan 6 | Same day | Chiniara EllenChief Legal Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −3.13K | $41.75 | −$130.6K | −5.4%54.8K after | |
| Dec 2, 2024 (view filing) | Dec 2 | Same day | Esposito PamelaDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −2.50K | $49.00 | −$122.5K | −100.0%0 after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Sep 17, 2024 (view filing) | Sep 17 | Same day | Esposito PamelaDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −13.5K | $48.28 | −$651.8K | −100.0%0 after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Aug 26, 2024 (view filing) | Aug 26 | Same day | Albers Jeffrey W.Director | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −5.00K | $49.10 | −$245.5K | −100.0%0 after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Aug 22, 2024 (view filing)5:06 PM ET | Aug 20 | 2 days | Biotechnology Value Fund L P and 9 othersDirector, Other: See Remarks and Footnotes | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Common Stock, $0.0001 par value | +358.3K | $40.75 | +$14.6M | –156.7K after | DerivativeA trade in a derivative security (option, warrant, restricted stock unit and so on). The value is the derivative's own price times the quantity.2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Aug 22, 2024 (view filing)4:03 PM ET | Aug 20 | 2 days | Baker Julian and 5 othersDirector | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in. | +1 | $46.41 | +$46.41 | 0.0%5.52M after | |
| Aug 22, 2024 (view filing)4:03 PM ET | Aug 21 | 1 day | Baker Julian and 5 othersDirector | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in. | +2.59M | $40.75 | +$105.7M | –9.63M after | DerivativeA trade in a derivative security (option, warrant, restricted stock unit and so on). The value is the derivative's own price times the quantity.2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Jul 16, 2024 (view filing) | Jul 15-16 | 1 day | Gollob JaredChief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −39.6K | $45.53 | −$1.80M | −29.3%95.5K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jul 9, 2024 (view filing) | Jul 9 | Same day | Booth BruceDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −454.0K | $38.21 | −$17.3M | −38.6%723.2K after | 10 lotsThis row combines 10 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jun 14, 2024 (view filing) | Jun 12-13 | 2 days | Booth BruceDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −26.9K | $35.27 | −$950.2K | −3.2%802.0K after | 6 lotsThis row combines 6 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jun 7, 2024 (view filing) | Jun 7 | Same day | Horobin JoannaDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −8.50K | $32.99 | −$280.4K | −100.0%0 after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| May 23, 2024 (view filing) | May 23 | Same day | Chadwick Jeremy GChief Operating Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −2.58K | $34.99 | −$90.1K | −5.5%44.2K after | |
| Mar 15, 2024 (view filing) | Mar 14-15 | 1 day | Booth BruceDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −127.4K | $40.25 | −$5.13M | −13.6%806.7K after | 11 lotsThis row combines 11 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Mar 15, 2024 (view filing) | Mar 14 | 1 day | Booth BruceDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −154 | $41.51 | −$6.39K | 0.0%819.2K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Mar 13, 2024 (view filing)7:53 PM ET | Mar 11-13 | 2 days | Atlas Venture Fund X, L.P. and 5 others10% Owner | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −292.0K | $42.20 | −$12.3M | −5.9%4.68M after | 6 lotsThis row combines 6 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Mar 13, 2024 (view filing)7:53 PM ET | Mar 11-13 | 2 days | Atlas Venture Fund X, L.P. and 5 others10% Owner | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −61.3K | $42.20 | −$2.59M | −6.9%828.8K after | 6 lotsThis row combines 6 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Mar 13, 2024 (view filing) | Mar 11-13 | 2 days | Booth BruceDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −353.4K | $42.20 | −$14.9M | −29.9%828.8K after | 12 lotsThis row combines 12 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Mar 4, 2024 (view filing) | Mar 4 | Same day | Gollob JaredChief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −3.34K | $41.85 | −$140.0K | −3.4%95.7K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average. |
| Mar 4, 2024 (view filing) | Mar 4 | Same day | Jacobs Bruce N.Chief Financial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −3.93K | $41.85 | −$164.7K | −2.7%142.4K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average. |
| Feb 29, 2024 (view filing) | Feb 27 | 2 days | Gollob JaredChief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −400 | $45.00 | −$18.0K | −0.5%74.7K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Feb 21, 2024 (view filing) | Feb 20-21 | 1 day | Albers Jeffrey W.Director | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −5.00K | $39.05 | −$195.3K | −100.0%0 after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Feb 9, 2024 (view filing) | Feb 9 | Same day | Gollob JaredChief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −46.1K | $35.50 | −$1.64M | −38.2%74.7K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jan 23, 2024 (view filing) | Jan 23 | Same day | Albers Jeffrey W.Director | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −10.0K | $30.05 | −$300.5K | −100.0%0 after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jan 9, 2024 (view filing)4:49 PM ET | Jan 5 | 4 days | Biotechnology Value Fund L P and 9 othersDirector, Other: See Remarks and Footnotes | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Common Stock, $0.0001 par value | +979.0K | $25.25 | +$24.7M | –52.7K after | DerivativeA trade in a derivative security (option, warrant, restricted stock unit and so on). The value is the derivative's own price times the quantity.3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average. |
| Jan 5, 2024 (view filing) | Jan 4 | 1 day | Chiniara EllenChief Legal Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −3.29K | $22.58 | −$74.4K | −8.8%34.2K after | |
| Nov 6, 2023 (view filing)6:07 PM ET | Nov 2-3 | 4 days | Biotechnology Value Fund L P and 9 othersDirector, Other: See Remarks and Footnotes | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Common Stock, $0.0001 par value | +414.1K | $12.80 | +$5.30M | New position294.6K after | 6 lotsThis row combines 6 trades of the same kind from one filing. The price is the value-weighted average. |
| Mar 3, 2023 (view filing) | Mar 2 | 1 day | Caughey ElaineChief Business Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −714 | $31.00 | −$22.1K | −3.6%19.0K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Mar 3, 2023 (view filing) | Mar 2 | 1 day | Gollob JaredChief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.30K | $31.00 | −$40.2K | −1.7%74.7K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Mar 3, 2023 (view filing) | Mar 2 | 1 day | Jacobs Bruce N.Chief Financial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.37K | $31.00 | −$42.5K | −1.3%104.6K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Jan 13, 2023 (view filing)5:08 PM ET | Jan 11-12 | 2 days | Biotechnology Value Fund L P and 9 othersDirector, Other: See Remarks and Footnotes | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Common Stock, $0.0001 par value | +41.0K | $30.51 | +$1.25M | +2.2%1.89M after | 4 lotsThis row combines 4 trades of the same kind from one filing. The price is the value-weighted average. |
| Jan 13, 2023 (view filing)4:50 PM ET | Jan 11-12 | 2 days | Atlas Venture Fund X, L.P. and 5 others10% Owner | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −98.8K | $30.22 | −$2.99M | −2.0%4.97M after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Jan 13, 2023 (view filing)4:50 PM ET | Jan 11-12 | 2 days | Atlas Venture Fund X, L.P. and 5 others10% Owner | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −27.7K | $30.22 | −$835.9K | −3.0%890.1K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Jan 13, 2023 (view filing) | Jan 11-12 | 2 days | Booth BruceDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −126.5K | $30.22 | −$3.82M | −12.4%890.1K after | 4 lotsThis row combines 4 trades of the same kind from one filing. The price is the value-weighted average. |
| Dec 16, 2022 (view filing)5:03 PM ET | Dec 14-15 | 2 days | Atlas Venture Fund X, L.P. and 5 others10% Owner | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −298.6K | $31.36 | −$9.36M | −5.6%5.07M after | 6 lotsThis row combines 6 trades of the same kind from one filing. The price is the value-weighted average. |
