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Jade Biosciences, Inc.

JBIO
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001798749

No open-market purchases or sales by Jade Biosciences, Inc. insiders were filed in the last 90 days; 153 institutions reported holding it in 13F filings for Q2 2026, worth $1.62B in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in Jade Biosciences, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
105
+27 vs. Q3 2025
Shares held
47.1M
+15.5M (+48.9%) vs. Q3 2025
Total value
$726.3M
+$453.4M (+166.2%) vs. Q3 2025
New holders
33
44 more added
Sold out
6
14 more reduced

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting JBIO on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 105 institutions
Q1 2021: 0 institutionsQ2 2021: 18 institutionsQ3 2021: 41 institutionsQ4 2021: 47 institutionsQ1 2022: 46 institutionsQ2 2022: 51 institutionsQ3 2022: 56 institutionsQ4 2022: 70 institutionsQ1 2023: 66 institutionsQ2 2023: 60 institutionsQ3 2023: 58 institutionsQ4 2023: 64 institutionsQ1 2024: 81 institutionsQ2 2024: 81 institutionsQ3 2024: 75 institutionsQ4 2024: 80 institutionsQ1 2025: 82 institutionsQ2 2025: 75 institutionsQ3 2025: 78 institutionsQ4 2025: 105 institutionsQ1 2026: 120 institutionsQ2 2026: 153 institutions
Value heldQ4 2025: $726.3M
Q1 2021: $0Q2 2021: $454.4MQ3 2021: $452.6MQ4 2021: $301.6MQ1 2022: $475.5MQ2 2022: $403.0MQ3 2022: $447.4MQ4 2022: $802.9MQ1 2023: $524.1MQ2 2023: $488.3MQ3 2023: $386.3MQ4 2023: $637.8MQ1 2024: $841.5MQ2 2024: $45.1MQ3 2024: $57.8MQ4 2024: $79.9MQ1 2025: $79.6MQ2 2025: $315.1MQ3 2025: $272.9MQ4 2025: $726.3MQ1 2026: $700.3MQ2 2026: $1.62B
Institutions holding JBIO and their total value by quarter
QuarterHoldersValue
Q2 2026153$1.62B
Q1 2026120$700.3M
Q4 2025105$726.3M
Q3 202578$272.9M
Q2 202575$315.1M
Q1 202582$79.6M
Q4 202480$79.9M
Q3 202475$57.8M
Q2 202481$45.1M
Q1 202481$841.5M
Q4 202364$637.8M
Q3 202358$386.3M
Q2 202360$488.3M
Q1 202366$524.1M
Q4 202270$802.9M
Q3 202256$447.4M
Q2 202251$403.0M
Q1 202246$475.5M
Q4 202147$301.6M
Q3 202141$452.6M
Q2 202118$454.4M
Q1 20210$0

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Jade Biosciences, Inc.; share changes are against Q3 2025.

Institutions holding JBIO in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Capital Advisors, Ltd. LLC6$00.00%00.0%Unchanged
Avion Wealth7$00.00%00.0%Unchanged
Assetmark, Inc1$150.00%00.0%Unchanged
Advisor Group Holdings, Inc.1$150.00%+1New
Jones Financial Companies LLLP2$310.00%00.0%Unchanged
SRS Capital Advisors, Inc.3$470.00%−152−98.1%Reduced
TFC Financial Management3$470.00%+3New
Torren Management, LLC5$770.00%+5New
Rothschild Investment LLC9$1390.00%+4+80.0%Added
SBI Securities Co., Ltd.14$2160.00%−13−48.1%Reduced
Larson Financial Group LLC23$3550.00%+23New
Allworth Financial LP24$3710.00%+24New
Simplex Trading, LLC59$9100.00%+59New
CWM, LLC39$1.00K0.00%−18−31.6%Reduced
Farther Finance Advisors, LLC77$1.19K0.00%00.0%Unchanged
EverSource Wealth Advisors, LLC89$1.37K0.00%+88+8,800.0%Added
The PNC Financial Services Group, Inc.93$1.44K0.00%+10+12.0%Added
Aster Capital Management (DIFC) Ltd95$1.47K0.00%+95New
Signaturefd, LLC128$1.98K0.00%+128New
UBS Asset Management Americas Inc210$3.24K0.00%+210New
GAMMA Investing LLC357$5.51K0.00%+175+96.2%Added
Versant Capital Management, Inc393$6.06K0.00%+393New
Nisa Investment Advisors, LLC471$7.27K0.00%+428+995.3%Added
STRS Ohio900$13.9K0.00%00.0%Unchanged
Tower Research Capital LLC (TRC)1,252$19.3K0.00%−653−34.3%Reduced
Citigroup Inc1,335$20.6K0.00%−257−16.1%Reduced
Amalgamated Bank1,454$22.0K0.00%+1,445+16,055.6%Added
Royal Bank of Canada1,491$23.0K0.00%+471+46.2%Added
Sterling Capital Management LLC2,667$41.2K0.00%+429+19.2%Added
California State Teachers Retirement System2,850$44.0K0.00%+819+40.3%Added
Ameritas Investment Partners, Inc.3,312$51.1K0.00%00.0%Unchanged
Legal & General Group Plc4,130$63.7K0.00%+1,176+39.8%Added
Group One Trading, L.P.4,195$64.7K0.00%−1,073−20.4%Reduced
Russell Investments Group, Ltd.5,932$91.5K0.00%+1,510+34.1%Added
BNP Paribas Arbitrage, SA9,869$152.3K0.00%−5,062−33.9%Reduced
Intech Investment Management LLC11,802$182.1K0.00%−2,320−16.4%Reduced
Police & Firemen's Retirement System of New Jersey12,097$186.7K0.00%+1,709+16.5%Added
Persistent Asset Partners Ltd12,469$192.4K0.09%+12,469New
Los Angeles Capital Management LLC21,570$212.5K0.00%+21,570New
Manufacturers Life Insurance Company, The14,012$216.2K0.00%+2,940+26.6%Added
New York State Common Retirement Fund14,622$225.6K0.00%+9,400+180.0%Added
Deltec Asset Management LLC15,756$243.1K0.04%00.0%Unchanged
Two Sigma Investments, LP16,496$254.5K0.00%−8,114−33.0%Reduced
Virtus Investment Advisers, Inc.17,759$274.0K0.07%+17,759New
JPMorgan Chase & Co20,599$317.8K0.00%+7,401+56.1%Added
ADAR1 Capital Management, LLC21,000$324.0K0.02%+21,000New
Mirae Asset Global ETFs Holdings Ltd.21,520$332.1K0.00%+6,298+41.4%Added
Tudor Investment Corp Et Al24,200$373.4K0.00%+24,200New
Price T Rowe Associates Inc25,169$389.0K0.00%+8,913+54.8%Added
MetLife Investment Management26,069$402.2K0.00%+12,785+96.2%Added
XTX Topco Ltd28,821$444.7K0.01%−11,476−28.5%Reduced
Quantinno Capital Management LP29,492$455.1K0.00%+2,517+9.3%Added
Deutsche Bank AG34,455$531.6K0.00%+4,859+16.4%Added
Citadel Advisors LLC36,055$556.3K0.00%+36,055New
Bank of America Corp37,512$578.8K0.00%+22,932+157.3%Added
Schroder Investment Management Group39,279$611.0K0.00%+39,279New
Alliancebernstein L.P.45,334$699.5K0.00%+33,280+276.1%Added
Rhumbline Advisers50,053$772.3K0.00%+7,269+17.0%Added
Wells Fargo & Company51,892$800.7K0.00%+27,022+108.7%Added
9823 Capital, L.P.53,191$820.7K0.57%+53,191New
Millennium Management LLC62,809$969.1K0.00%+62,809New
Goldman Sachs Group Inc65,340$1.01M0.00%−97,371−59.8%Reduced
Connor, Clark & Lunn Investment Management Ltd.67,230$1.04M0.00%+67,230New
Renaissance Technologies LLC69,601$1.07M0.00%+69,601New
Barclays PLC72,194$1.11M0.00%+26,427+57.7%Added
Morgan Stanley79,767$1.23M0.00%+25,526+47.1%Added
Boothbay Fund Management, LLC81,148$1.25M0.03%+81,148New
Woodline Partners LP82,056$1.27M0.00%+82,056New
UBS Group AG96,786$1.49M0.00%+76,955+388.1%Added
Wellington Management Group LLP102,620$1.58M0.00%−4,933−4.6%Reduced
Sofinnova Investments, Inc.107,391$1.66M0.07%00.0%Unchanged
Bank of New York Mellon Corp114,906$1.77M0.00%+32,555+39.5%Added
Nuveen, LLC124,545$1.92M0.00%+81,797+191.3%Added
Charles Schwab Investment Management Inc125,772$1.94M0.00%+32,522+34.9%Added
Ameriprise Financial Inc187,254$2.89M0.00%+187,254New
Invesco Ltd.199,727$3.08M0.00%+165,151+477.6%Added
Northern Trust Corp274,101$4.23M0.00%+44,520+19.4%Added
ExodusPoint Capital Management, LP287,587$4.44M0.05%+287,587New
Caption Management, LLC297,095$4.58M0.20%+297,095New
Ikarian Capital, LLC300,000$4.63M0.60%+300,000New
Logos Global Management LP395,000$6.09M0.41%−230,000−36.8%Reduced
Opaleye Management Inc.427,608$6.60M0.87%+427,608New
OrbiMed Advisors LLC531,163$8.20M0.17%00.0%Unchanged
Point72 Asset Management, L.P.558,474$8.62M0.01%+558,474New
State Street Corp642,921$9.92M0.00%+143,634+28.8%Added
Affinity Asset Advisors, LLC714,956$11.0M0.79%+649,639+994.6%Added
Soleus Capital Management, L.P.796,744$12.3M0.52%00.0%Unchanged
Great Point Partners LLC806,273$12.4M4.03%+173,674+27.5%Added
Geode Capital Management, LLC841,808$13.0M0.00%+175,893+26.4%Added
Standard Life Aberdeen plc867,284$13.4M0.02%+867,284New
Marshall Wace, LLP875,273$13.5M0.01%+837,193+2,198.5%Added
Driehaus Capital Management LLC887,179$13.7M0.09%−368,619−29.4%Reduced
Samsara BioCapital, LLC968,798$14.9M1.54%+437,635+82.4%Added
Avidity Partners Management LP1,400,708$21.6M6.23%+273,522+24.3%Added
RTW Investments, LP1,449,273$22.4M0.22%00.0%Unchanged
Versant Venture Management, LLC1,525,820$23.5M15.59%00.0%Unchanged
Remedium Capital Partners, LLC1,577,750$24.3M14.30%+1,577,750New
Baker Bros. Advisors LP1,641,137$25.3M0.15%+1,641,137New
Vanguard Group Inc2,095,767$32.3M0.00%+369,023+21.4%Added
BlackRock, Inc.2,870,313$44.3M0.00%+720,110+33.5%Added