| Mar 16, 2026 (view filing) | Mar 16 | Same day | Callos AndrewEVP, Chief Commercial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.71K | $61.03 | −$104.3K | −3.6%46.1K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Mar 10, 2026 (view filing) | Mar 9 | 1 day | Callos AndrewEVP, Chief Commercial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −2.58K | $60.72 | −$156.8K | −5.1%47.9K after | |
| Mar 10, 2026 (view filing) | Mar 9 | 1 day | Malik Fady IbrahamEVP Research & Development | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −2.91K | $60.72 | −$176.5K | −2.1%138.6K after | |
| Mar 10, 2026 (view filing) | Mar 9 | 1 day | Blum Robert IPresident & CEO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −7.93K | $60.72 | −$481.6K | −2.0%391.7K after | |
| Mar 5, 2026 (view filing) | Mar 5 | Same day | Callos AndrewEVP, Chief Commercial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −26.0K | $61.87 | −$1.61M | −34.0%50.4K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Mar 2, 2026 (view filing) | Mar 2 | Same day | Parshall B LynneDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −5.00K | $61.21 | −$306.1K | −21.8%17.9K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Mar 2, 2026 (view filing) | Mar 2 | Same day | Callos AndrewEVP, Chief Commercial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −886 | $61.62 | −$54.6K | −1.7%50.4K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Feb 5, 2026 (view filing) | Feb 5 | Same day | Callos AndrewEVP, Chief Commercial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −15.0K | $61.93 | −$929.0K | −22.9%50.4K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Feb 2, 2026 (view filing) | Feb 2 | Same day | Callos AndrewEVP, Chief Commercial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −886 | $62.10 | −$55.0K | −1.7%50.4K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jan 5, 2026 (view filing) | Jan 5 | Same day | Callos AndrewEVP, Chief Commercial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −15.0K | $60.28 | −$904.2K | −22.9%50.4K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jan 2, 2026 (view filing) | Jan 2 | Same day | Callos AndrewEVP, Chief Commercial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.80K | $62.62 | −$112.6K | −3.4%50.4K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Dec 30, 2025 (view filing) | Dec 29 | 1 day | Callos AndrewEVP, Chief Commercial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.81K | $62.44 | −$113.0K | −3.4%51.4K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Dec 23, 2025 (view filing) | Dec 22 | 1 day | Wierenga WendellDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −20.0K | $66.14 | −$1.32M | −38.1%32.4K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Dec 16, 2025 (view filing) | Dec 16 | Same day | Malik Fady IbrahamEVP Research & Development | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −2.20K | $61.24 | −$134.7K | −1.6%138.6K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Dec 8, 2025 (view filing) | Dec 8 | Same day | Callos AndrewEVP, Chief Commercial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.04K | $65.96 | −$68.7K | −2.0%50.7K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Dec 5, 2025 (view filing) | Dec 5 | Same day | Callos AndrewEVP, Chief Commercial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −52.5K | $65.95 | −$3.46M | −50.9%50.7K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Dec 2, 2025 (view filing) | Dec 2 | Same day | Henderson John TDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −8.75K | $63.90 | −$559.1K | −10.5%74.6K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Dec 2, 2025 (view filing) | Dec 2 | Same day | Malik Fady IbrahamEVP Research & Development | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −2.20K | $63.89 | −$140.6K | −1.5%140.6K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Dec 2, 2025 (view filing) | Dec 1 | 1 day | Kaye Edward M. MDDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −28.1K | $66.72 | −$1.87M | −73.8%9.98K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Dec 2, 2025 (view filing) | Dec 1 | 1 day | Harrington Robert ArthurDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −2.15K | $66.80 | −$143.6K | −10.4%18.5K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Nov 19, 2025 (view filing) | Nov 19 | Same day | Parshall B LynneDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −5.00K | $64.73 | −$323.6K | −17.9%22.9K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Nov 18, 2025 (view filing) | Nov 18 | Same day | Malik Fady IbrahamEVP Research & Development | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −2.20K | $66.45 | −$146.2K | −1.5%140.6K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Nov 12, 2025 (view filing) | Nov 11 | 1 day | Kaye Edward M. MDDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −5.17K | $65.08 | −$336.8K | −34.2%9.98K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Nov 4, 2025 (view filing) | Nov 4 | Same day | Malik Fady IbrahamEVP Research & Development | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −2.29K | $59.55 | −$136.7K | −1.6%140.6K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Oct 30, 2025 (view filing) | Oct 30 | Same day | Blum Robert IPresident & CEO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −5.00K | $62.86 | −$314.3K | −1.4%358.1K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Oct 27, 2025 (view filing) | Oct 27 | Same day | Wierenga WendellDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −4.38K | $58.68 | −$256.7K | −11.9%32.4K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Oct 21, 2025 (view filing) | Oct 21 | Same day | Malik Fady IbrahamEVP Research & Development | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −2.10K | $58.22 | −$122.6K | −1.5%140.6K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Oct 16, 2025 (view filing) | Oct 16 | Same day | Blum Robert IPresident & CEO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −5.00K | $60.03 | −$300.1K | −1.4%363.1K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Oct 7, 2025 (view filing) | Oct 7 | Same day | Malik Fady IbrahamEVP Research & Development | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −2.00K | $60.56 | −$121.1K | −1.4%140.6K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Oct 6, 2025 (view filing) | Oct 6 | Same day | Kaye Edward M. MDDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −6.76K | $60.00 | −$405.4K | −40.9%9.78K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Oct 1, 2025 (view filing) | Oct 1 | Same day | Blum Robert IPresident & CEO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −5.00K | $55.05 | −$275.3K | −1.3%368.1K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Sep 30, 2025 (view filing) | Sep 30 | Same day | Kaye Edward M. MDDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −6.70K | $55.08 | −$368.8K | −28.8%16.5K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Sep 23, 2025 (view filing) | Sep 23 | Same day | Malik Fady IbrahamEVP Research & Development | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −2.00K | $49.28 | −$98.6K | −1.4%140.6K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Sep 15, 2025 (view filing) | Sep 15 | Same day | Blum Robert IPresident & CEO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −5.00K | $49.77 | −$248.8K | −1.3%373.1K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Sep 10, 2025 (view filing) | Sep 9 | 1 day | Malik Fady IbrahamEVP Research & Development | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −2.00K | $51.29 | −$102.6K | −1.4%140.6K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Sep 2, 2025 (view filing) | Sep 2 | Same day | Kaye Edward M. MDDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −6.76K | $50.00 | −$337.8K | −22.5%23.2K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Sep 2, 2025 (view filing) | Sep 2 | Same day | Harrington Robert ArthurDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −2.15K | $48.67 | −$104.6K | −9.5%20.5K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Sep 2, 2025 (view filing) | Sep 2 | Same day | Blum Robert IPresident & CEO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −5.00K | $48.76 | −$243.8K | −1.3%378.1K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Aug 19, 2025 (view filing) | Aug 19 | Same day | Malik Fady IbrahamEVP Research & Development | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −2.00K | $38.31 | −$76.6K | −1.4%140.6K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Aug 15, 2025 (view filing) | Aug 15 | Same day | Blum Robert IPresident & CEO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −5.00K | $38.42 | −$192.1K | −1.3%383.1K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Aug 5, 2025 (view filing) | Aug 5 | Same day | Malik Fady IbrahamEVP Research & Development | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −2.00K | $36.34 | −$72.7K | −1.4%140.6K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jul 31, 2025 (view filing) | Jul 29 | 2 days | Blum Robert IPresident & CEO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −5.00K | $36.45 | −$182.3K | −1.3%388.1K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jul 23, 2025 (view filing) | Jul 22 | 1 day | Malik Fady IbrahamEVP Research & Development | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −2.00K | $37.47 | −$74.9K | −1.4%140.6K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jul 15, 2025 (view filing) | Jul 14 | 1 day | Blum Robert IPresident & CEO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −5.00K | $38.15 | −$190.8K | −1.3%393.1K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jul 8, 2025 (view filing) | Jul 8 | Same day | Malik Fady IbrahamEVP Research & Development | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −2.00K | $33.76 | −$67.5K | −1.4%140.6K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jul 2, 2025 (view filing) | Jul 1 | 1 day | Blum Robert IPresident & CEO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −5.00K | $33.55 | −$167.8K | −1.2%398.1K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jun 17, 2025 (view filing) | Jun 17 | Same day | Malik Fady IbrahamEVP Research & Development | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −2.00K | $32.91 | −$65.8K | −1.4%140.6K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jun 16, 2025 (view filing) | Jun 16 | Same day | Blum Robert IPresident & CEO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −5.00K | $33.80 | −$169.0K | −1.2%403.1K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jun 5, 2025 (view filing) | Jun 5 | Same day | Kaye Edward M. MDDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −3.64K | $32.10 | −$116.7K | −10.9%29.7K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jun 5, 2025 (view filing) | Jun 5 | Same day | Callos AndrewEVP, Chief Commercial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −8.66K | $32.04 | −$277.4K | −14.3%52.0K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
