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Clearside Biomedical, Inc.

CLSDDelisted Dec 8, 2025
Industry
Pharmaceutical Preparations
SEC CIK
0001539029

Clearside Biomedical, Inc. was delisted on Dec 8, 2025; its insiders filed their last Form 4 on Feb 24, 2025; 26 institutions reported holding it in 13F filings for Q3 2025, worth $2.18M in total; no superinvestor held it.

13F holders, Q4 2021

Institutional positions in Clearside Biomedical, Inc. as of Dec 31, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
67
+2 vs. Q3 2021
Shares held
21.0M
+815.8K (+4.0%) vs. Q3 2021
Total value
$57.8M
−$63.4M (−52.3%) vs. Q3 2021
New holders
18
23 more added
Sold out
16
14 more reduced

1 institution that held it in Q3 2021 haven't filed for Q4 2021 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting CLSD on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2021: 67 institutions
Q1 2021: 52 institutionsQ2 2021: 53 institutionsQ3 2021: 66 institutionsQ4 2021: 67 institutionsQ1 2022: 60 institutionsQ2 2022: 53 institutionsQ3 2022: 54 institutionsQ4 2022: 53 institutionsQ1 2023: 51 institutionsQ2 2023: 54 institutionsQ3 2023: 46 institutionsQ4 2023: 48 institutionsQ1 2024: 52 institutionsQ2 2024: 49 institutionsQ3 2024: 49 institutionsQ4 2024: 44 institutionsQ1 2025: 44 institutionsQ2 2025: 45 institutionsQ3 2025: 26 institutionsQ4 2025: 1 institutionQ1 2026: 1 institutionQ2 2026: 1 institution
Value heldQ4 2021: $57.8M
Q1 2021: $43.8MQ2 2021: $95.8MQ3 2021: $121.5MQ4 2021: $57.8MQ1 2022: $37.5MQ2 2022: $20.1MQ3 2022: $13.6MQ4 2022: $10.2MQ1 2023: $9.09MQ2 2023: $9.62MQ3 2023: $6.82MQ4 2023: $9.06MQ1 2024: $23.8MQ2 2024: $17.9MQ3 2024: $12.7MQ4 2024: $8.97MQ1 2025: $8.09MQ2 2025: $7.51MQ3 2025: $2.18MQ4 2025: $19.1KQ1 2026: $7.87KQ2 2026: $3.26K
Institutions holding CLSD and their total value by quarter
QuarterHoldersValue
Q2 20261$3.26K
Q1 20261$7.87K
Q4 20251$19.1K
Q3 202526$2.18M
Q2 202545$7.51M
Q1 202544$8.09M
Q4 202444$8.97M
Q3 202449$12.7M
Q2 202449$17.9M
Q1 202452$23.8M
Q4 202348$9.06M
Q3 202346$6.82M
Q2 202354$9.62M
Q1 202351$9.09M
Q4 202253$10.2M
Q3 202254$13.6M
Q2 202253$20.1M
Q1 202260$37.5M
Q4 202167$57.8M
Q3 202166$121.5M
Q2 202153$95.8M
Q1 202152$43.8M

Institutions, Q4 2021

Shares, value and share of portfolio for each institution holding Clearside Biomedical, Inc.; share changes are against Q3 2021.

Institutions holding CLSD in Q4 2021
InstitutionSharesValue% of portfolioChange in sharesAction
Wells Fargo & Company51$00.00%−305−85.7%Reduced
FMR LLC127$00.00%−1−0.8%Reduced
Captrust Financial Advisors100$00.00%+100New
Barclays PLC500$1.00K0.00%−16,548−97.1%Reduced
Royal Bank of Canada1,018$3.00K0.00%+1,018New
Cutler Group LP2,100$5.00K0.00%00.0%Unchanged
Bank of America Corp4,213$12.0K0.00%+1,344+46.8%Added
The PNC Financial Services Group, Inc.5,586$15.0K0.00%00.0%Unchanged
Simplex Trading, LLC6,017$16.0K0.00%+6,017New
JPMorgan Chase & Co7,260$20.0K0.00%+5,260+263.0%Added
Citigroup Inc9,863$27.0K0.00%+6,464+190.2%Added
UBS Group AG10,137$28.0K0.00%+3,359+49.6%Added
PDT Partners, LLC10,616$29.0K0.00%+10,616New
Walleye Trading LLC11,456$32.0K0.00%+11,456New
Price T Rowe Associates Inc11,900$33.0K0.00%+11,900New
Advisor Group Holdings, Inc.12,350$34.0K0.00%+3,000+32.1%Added
Tower Research Capital LLC (TRC)12,635$35.0K0.00%+9,688+328.7%Added
Alpine Global Management, LLC13,743$38.0K0.01%+13,743New
Exencial Wealth Advisors, LLC14,064$39.0K0.00%+14,064New
Virtu Financial LLC14,573$40.0K0.00%+14,573New
BNP Paribas Arbitrage, SA14,623$40.2K0.00%+14,622+1,462,200.0%Added
Integrated Advisors Network LLC15,700$43.0K0.00%00.0%Unchanged
Old Mission Capital LLC16,362$45.0K0.00%+16,362New
Balyasny Asset Management LLC18,763$52.0K0.00%+18,763New
Stifel Financial Corp19,480$54.0K0.00%+4,350+28.8%Added
Charles Schwab Investment Management Inc20,216$56.0K0.00%00.0%Unchanged
Jane Street Group, LLC20,792$57.0K0.00%+20,792New
Ameritas Advisory Services, LLC20,810$57.0K0.00%+20,810New
XTX Topco Ltd22,581$62.0K0.04%+22,581New
Private Advisor Group, LLC23,000$63.0K0.00%00.0%Unchanged
Curi Capital25,000$68.0K0.01%00.0%Unchanged
Newman Dignan & Sheerar, Inc.25,823$71.0K0.02%+4,300+20.0%Added
Synovus Financial Corp28,071$77.0K0.00%00.0%Unchanged
ExodusPoint Capital Management, LP29,385$81.0K0.00%+5,900+25.1%Added
Golden State Equity Partners30,527$84.0K0.04%+30,527New
Bank of New York Mellon Corp30,795$85.0K0.00%00.0%Unchanged
Cambridge Investment Research Advisors, Inc.31,900$88.0K0.00%−10,950−25.6%Reduced
Caxton Associates LP35,916$99.0K0.01%−30,653−46.0%Reduced
Wedbush Securities Inc36,239$100.0K0.00%+36,239New
Ameriprise Financial Inc38,542$106.0K0.00%+500+1.3%Added
Citadel Advisors LLC38,682$107.0K0.00%−199,996−83.8%Reduced
Cubist Systematic Strategies, LLC52,947$146.0K0.00%−27,020−33.8%Reduced
Northeast Financial Consultants Inc53,000$146.0K0.01%+40,000+307.7%Added
Signaturefd, LLC54,177$149.0K0.00%−285−0.5%Reduced
Principal Financial Group Inc65,344$180.0K0.00%+65,344New
Jump Financial, LLC67,976$187.0K0.01%+29,807+78.1%Added
Goldman Sachs Group Inc79,462$219.0K0.00%+32,646+69.7%Added
Northern Trust Corp96,786$266.0K0.00%−6,437−6.2%Reduced
Walleye Capital LLC103,771$285.0K0.01%+103,771New
Franklin Resources Inc111,613$307.0K0.00%−287−0.3%Reduced
Group One Trading, L.P.162,852$448.0K0.01%+134,650+477.4%Added
First Manhattan Co175,000$481.0K0.00%00.0%Unchanged
State Street Corp183,888$506.0K0.00%00.0%Unchanged
Susquehanna International Group, LLP276,850$761.0K0.00%−99,959−26.5%Reduced
Bridgeway Capital Management, LLC316,600$871.0K0.02%00.0%Unchanged
Millennium Management LLC370,498$1.02M0.00%+105,026+39.6%Added
Renaissance Technologies LLC429,217$1.18M0.00%+327,728+322.9%Added
Geode Capital Management, LLC486,642$1.34M0.00%00.0%Unchanged
Two Sigma Advisers, LP879,900$2.42M0.01%−131,500−13.0%Reduced
Two Sigma Investments, LP940,299$2.59M0.01%+112,800+13.6%Added
BlackRock Inc.1,219,389$3.35M0.00%+415,037+51.6%Added
Morgan Stanley1,606,405$4.42M0.00%+799,850+99.2%Added
Assenagon Asset Management S.A.1,634,412$4.50M0.02%+1,615,538+8,559.6%Added
Vanguard Group Inc2,175,152$5.98M0.00%−3,020−0.1%Reduced
ACT Capital Management, LLC2,483,500$6.83M4.94%+16,000+0.6%Added
Carmignac Gestion2,485,652$6.84M0.10%+10,000+0.4%Added
RTW Investments, LP3,806,018$10.5M0.15%−400,747−9.5%Reduced
Acuta Capital Partners, LLC0$00.00%−1,316,268−100.0%Sold out
AJU IB Investment Co., Ltd.0$00.00%−293,555−100.0%Sold out
Invesco Ltd.0$00.00%−277,161−100.0%Sold out
EAM Investors, LLC0$00.00%−247,561−100.0%Sold out
Marshall Wace, LLP0$00.00%−53,474−100.0%Sold out
Trexquant Investment LP0$00.00%−43,768−100.0%Sold out
Dynamic Technology Lab Private Ltd0$00.00%−39,745−100.0%Sold out
Susquehanna Fundamental Investments, LLC0$00.00%−29,360−100.0%Sold out
Qube Research & Technologies Ltd0$00.00%−25,815−100.0%Sold out
Squarepoint Ops LLC0$00.00%−15,466−100.0%Sold out
Capstone Investment Advisors, LLC0$00.00%−11,856−100.0%Sold out
Vestor Capital, LLC0$00.00%−9,000−100.0%Sold out
Dorsey Wright & Associates0$00.00%−9,034−100.0%Sold out
Core Wealth Advisors, Inc.0$00.00%−500−100.0%Sold out
Harbour Investments, Inc.0$00.00%−400−100.0%Sold out
Federated Hermes, Inc.0$00.00%−66−100.0%Sold out
Ameritas Investment Company, LLC––––Not filed