| Aug 19, 2021 (view filing) | Aug 17 | 2 days | Hurley ArielPrincipal Accounting Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.35K | $91.93 | −$124.1K | −11.8%10.1K after | |
| Aug 23, 2021 (view filing) | Aug 19 | 4 days | Albers Jeffrey W.CEO and President | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −25.0K | $92.68 | −$2.32M | −12.7%172.4K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Sep 15, 2021 (view filing) | Sep 13 | 2 days | Haviland KateChief Operating Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.00K | $99.94 | −$99.9K | −1.8%53.9K after | 5 lotsThis row combines 5 trades of the same kind from one filing. The price is the value-weighted average. |
| Sep 15, 2021 (view filing) | Sep 13 | 2 days | Hurley ArielPrincipal Accounting Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −600 | $100.00 | −$60.0K | −5.6%10.1K after | |
| Sep 17, 2021 (view filing) | Jun 2 | 107 daysLateFiled more than 2 business days after the trade (the Form 4 deadline). A few cases, such as trades a broker makes under a 10b5-1 plan, have a longer deadline, so this flag comes from the dates alone and does not mean a rule was broken. | Hewes L. BeckerChief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.29K | $89.03 | −$115.0K | −4.2%29.3K after | |
| Sep 17, 2021 (view filing) | Sep 15 | 2 days | Hewes L. BeckerChief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −11.8K | $101.17 | −$1.20M | −31.1%26.2K after | 4 lotsThis row combines 4 trades of the same kind from one filing. The price is the value-weighted average. |
| Sep 27, 2021 (view filing) | Sep 23 | 4 days | Durso-Bumpus DebraChief People Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −848 | $110.01 | −$93.3K | −2.7%30.9K after | |
| Sep 27, 2021 (view filing) | Sep 23 | 4 days | McCain Tracey LEVP and Chief Legal Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −25.0K | $108.85 | −$2.72M | −42.9%33.3K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average. |
| Sep 27, 2021 (view filing) | Sep 23 | 4 days | Hurley ArielPrincipal Accounting Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −600 | $110.00 | −$66.0K | −5.6%10.1K after | |
| Oct 7, 2021 (view filing) | Oct 5 | 2 days | Namouni FouadPresident, R & D | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −3.24K | $98.18 | −$318.2K | −7.1%42.3K after | |
| Oct 19, 2021 (view filing) | Oct 15 | 4 days | Hewes L. BeckerChief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −729 | $102.66 | −$74.8K | −2.7%26.2K after | |
| Nov 3, 2021 (view filing) | Nov 1 | 2 days | Albers Jeffrey W.CEO and President | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −5.00K | $115.16 | −$575.8K | −2.6%188.4K after | |
| Nov 3, 2021 (view filing) | Nov 1 | 2 days | Durso-Bumpus DebraChief People Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −5.18K | $113.03 | −$585.2K | −14.4%30.9K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average. |
| Nov 5, 2021 (view filing) | Nov 3 | 2 days | McCain Tracey LEVP and Chief Legal Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −5.00K | $110.56 | −$552.8K | −13.1%33.3K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Nov 17, 2021 (view filing) | Nov 15 | 2 days | Hewes L. BeckerChief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −729 | $115.49 | −$84.2K | −2.7%26.2K after | |
| Nov 17, 2021 (view filing) | Nov 15 | 2 days | Albers Jeffrey W.CEO and President | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −30.0K | $114.50 | −$3.44M | −13.7%188.4K after | 4 lotsThis row combines 4 trades of the same kind from one filing. The price is the value-weighted average. |
| Nov 18, 2021 (view filing) | Nov 16 | 2 days | Hurley ArielPrincipal Accounting Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.95K | $114.28 | −$222.8K | −16.2%10.1K after | |
| Dec 9, 2021 (view filing) | Dec 7 | 2 days | McCain Tracey LEVP and Chief Legal Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −5.00K | $97.30 | −$486.5K | −13.0%33.4K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average. |
| Dec 15, 2021 (view filing) | Dec 13 | 2 days | Haviland KateChief Operating Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.00K | $98.30 | −$98.3K | −1.8%53.9K after | 4 lotsThis row combines 4 trades of the same kind from one filing. The price is the value-weighted average. |
| Dec 17, 2021 (view filing) | Dec 15 | 2 days | Hewes L. BeckerChief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −729 | $100.00 | −$72.9K | −2.7%26.2K after | |
| Mar 7, 2022 (view filing) | Mar 3 | 4 days | Goldberg Mark AlanDirector | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in. | +5.00K | $59.98 | +$299.9K | +86.0%10.8K after | |
| Mar 8, 2022 (view filing) | Mar 3-7 | 5 daysLateFiled more than 2 business days after the trade (the Form 4 deadline). A few cases, such as trades a broker makes under a 10b5-1 plan, have a longer deadline, so this flag comes from the dates alone and does not mean a rule was broken. | Durso-Bumpus DebraCHIEF PEOPLE OFFICER | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −2.54K | $58.59 | −$148.7K | −5.9%40.8K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Mar 8, 2022 (view filing) | Mar 3-7 | 5 daysLateFiled more than 2 business days after the trade (the Form 4 deadline). A few cases, such as trades a broker makes under a 10b5-1 plan, have a longer deadline, so this flag comes from the dates alone and does not mean a rule was broken. | Haviland KateCHIEF OPERATING OFFICER | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −2.77K | $58.72 | −$162.5K | −2.9%91.2K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Mar 8, 2022 (view filing) | Mar 7 | 1 day | Hewes L. BeckerCHIEF MEDICAL OFFICER | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.05K | $56.19 | −$58.8K | −3.0%33.9K after | |
| Mar 8, 2022 (view filing) | Mar 3-7 | 5 daysLateFiled more than 2 business days after the trade (the Form 4 deadline). A few cases, such as trades a broker makes under a 10b5-1 plan, have a longer deadline, so this flag comes from the dates alone and does not mean a rule was broken. | Landsittel MichaelCHIEF FINANCIAL OFFICER | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −2.38K | $58.47 | −$138.9K | −5.7%39.0K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Mar 8, 2022 (view filing) | Mar 3-7 | 5 daysLateFiled more than 2 business days after the trade (the Form 4 deadline). A few cases, such as trades a broker makes under a 10b5-1 plan, have a longer deadline, so this flag comes from the dates alone and does not mean a rule was broken. | McCain Tracey LEVP AND CHIEF LEGAL OFFICER | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −2.71K | $58.70 | −$159.3K | −5.9%43.2K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Mar 8, 2022 (view filing) | Mar 3-7 | 5 daysLateFiled more than 2 business days after the trade (the Form 4 deadline). A few cases, such as trades a broker makes under a 10b5-1 plan, have a longer deadline, so this flag comes from the dates alone and does not mean a rule was broken. | Murray Christopher K.SVP, TECHNICAL OPERATIONS | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.57K | $58.96 | −$92.5K | −6.2%23.8K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Mar 8, 2022 (view filing) | Mar 7 | 1 day | Namouni FouadPRESIDENT, R & D | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.05K | $56.19 | −$58.8K | −1.8%56.3K after | |
| Mar 8, 2022 (view filing) | Mar 3-7 | 5 daysLateFiled more than 2 business days after the trade (the Form 4 deadline). A few cases, such as trades a broker makes under a 10b5-1 plan, have a longer deadline, so this flag comes from the dates alone and does not mean a rule was broken. | Rossi ChristinaCHIEF COMMERCIAL OFFICER | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −2.24K | $58.37 | −$131.0K | −4.8%44.5K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Mar 8, 2022 (view filing) | Mar 3-7 | 5 daysLateFiled more than 2 business days after the trade (the Form 4 deadline). A few cases, such as trades a broker makes under a 10b5-1 plan, have a longer deadline, so this flag comes from the dates alone and does not mean a rule was broken. | Albers Jeffrey W.CEO AND PRESIDENT | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −32.7K | $57.90 | −$1.89M | −15.1%183.2K after | 6 lotsThis row combines 6 trades of the same kind from one filing. The price is the value-weighted average. |
| Mar 8, 2022 (view filing) | Mar 3-7 | 5 daysLateFiled more than 2 business days after the trade (the Form 4 deadline). A few cases, such as trades a broker makes under a 10b5-1 plan, have a longer deadline, so this flag comes from the dates alone and does not mean a rule was broken. | Hurley ArielPRINCIPAL ACCOUNTING OFFICER | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.02K | $59.24 | −$60.3K | −7.8%12.0K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Mar 14, 2022 (view filing) | Mar 10 | 4 days | Hurley ArielPRINCIPAL ACCOUNTING OFFICER | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −2.34K | $57.15 | −$133.7K | −19.6%9.62K after | |
| Mar 18, 2022 (view filing) | Mar 16 | 2 days | Hewes L. BeckerCHIEF MEDICAL OFFICER | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −2.22K | $60.00 | −$133.1K | −6.5%31.7K after | |
| Mar 23, 2022 (view filing) | Nov 3, 2021 | 140 daysLateFiled more than 2 business days after the trade (the Form 4 deadline). A few cases, such as trades a broker makes under a 10b5-1 plan, have a longer deadline, so this flag comes from the dates alone and does not mean a rule was broken. | Rossi ChristinaCHIEF COMMERCIAL OFFICER | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −511 | $110.85 | −$56.6K | −1.1%44.0K after | |
| Apr 8, 2022 (view filing) | Apr 6 | 2 days | Albers Jeffrey W.CEO AND PRESIDENT | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −5.00K | $70.11 | −$350.6K | −2.7%183.2K after | |
| May 18, 2022 (view filing) | May 16 | 2 days | Albers Jeffrey W.Director | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −20.0K | $55.89 | −$1.12M | −9.8%183.2K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average. |
| Jun 8, 2022 (view filing) | Jun 6-7 | 2 days | Hewes L. BeckerCHIEF MEDICAL OFFICER | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −4.38K | $59.93 | −$262.2K | −13.8%27.3K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Jun 8, 2022 (view filing) | Jun 6 | 2 days | Carter Percy H.CHIEF SCIENTIFIC OFFICER | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.91K | $59.76 | −$114.0K | −6.2%28.7K after | |
| Jun 30, 2022 (view filing) | Jul 13, 2021 | 352 daysLateFiled more than 2 business days after the trade (the Form 4 deadline). A few cases, such as trades a broker makes under a 10b5-1 plan, have a longer deadline, so this flag comes from the dates alone and does not mean a rule was broken. | Demetri GeorgeDirector | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in. | +10 | $82.66 | +$826.6 | +0.2%5.82K after | |
| Jun 30, 2022 (view filing) | Mar 17 | 105 daysLateFiled more than 2 business days after the trade (the Form 4 deadline). A few cases, such as trades a broker makes under a 10b5-1 plan, have a longer deadline, so this flag comes from the dates alone and does not mean a rule was broken. | Demetri GeorgeDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −10 | $58.56 | −$585.6 | −0.2%5.81K after | |
| Aug 8, 2022 (view filing) | Aug 4-5 | 4 days | Murray Christopher K.SVP, TECHNICAL OPERATIONS | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −5.00K | $62.72 | −$313.6K | −21.0%18.8K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Aug 10, 2022 (view filing) | Aug 8 | 2 days | Albers Jeffrey W.Director | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −10.0K | $70.07 | −$700.7K | −5.2%183.2K after | |
| Aug 18, 2022 (view filing) | Aug 16 | 2 days | Albers Jeffrey W.Director | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −20.0K | $68.41 | −$1.37M | −9.8%183.2K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average. |
| Aug 23, 2022 (view filing) | Aug 19-22 | 4 days | Albers Jeffrey W.Director | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −10.0K | $70.45 | −$704.5K | −5.2%183.2K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average. |
| Aug 26, 2022 (view filing) | Aug 24 | 2 days | Durso-Bumpus DebraCHIEF PEOPLE OFFICER | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −5.00K | $75.11 | −$375.6K | −10.9%40.8K after | |
| Oct 5, 2022 (view filing) | Oct 4 | 1 day | Namouni FouadPRESIDENT, R & D | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −3.48K | $67.30 | −$234.0K | −6.2%52.8K after | |
| Nov 7, 2022 (view filing) | Nov 3 | 4 days | Haviland KateCHIEF EXECUTIVE OFFICER | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in. | +1.10K | $43.98 | +$48.4K | +1.2%92.3K after | |
| Nov 7, 2022 (view filing) | Nov 3 | 4 days | Rossi ChristinaCHIEF OPERATING OFFICER | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −533 | $45.24 | −$24.1K | −1.2%43.4K after | |
| Dec 7, 2022 (view filing) | Dec 5 | 2 days | Albers Jeffrey W.Director | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −20.0K | $50.09 | −$1.00M | −9.8%183.2K after | |
| Mar 8, 2023 (view filing) | Mar 6 | 2 days | Haviland KateCHIEF EXECUTIVE OFFICER | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −6.64K | $45.69 | −$303.4K | −5.0%125.6K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
