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VR Adviser, LLC

SEC CIK
0001615982
Latest filing
Aug 14, 2026

Holdings in Q4 2022

Holdings as of Dec 31, 2022, filed May 15, 2023. Long positions only; changes compare share counts with Q3 2022.

Institution overview
Positions
28
−3 vs. Q3 2022
Portfolio value
$593.6M
−$54.5M (−8.4%) vs. Q3 2022
Filed
May 15, 2023
AmendedSEC
Holdings of VR Adviser, LLC in Q4 2022
SecurityClassSharesValue% of portfolioShare changeActionHistory
RLYBRallybio CorpCOM268,532$1.76M0.3%00.0%UnchangedHistory
Affimed N VN01045108COM1,428,571$1.77M0.3%00.0%Unchanged–
ATYRaTYR PHARMA INCCOM NEW1,171,436$2.57M0.4%−227,453−16.3%ReducedHistory
INZYInozyme Pharma, Inc.COM2,709,987$2.85M0.5%00.0%UnchangedHistory
LYRALyra Therapeutics, Inc.COM924,170$2.90M0.5%00.0%UnchangedHistory
FULCFulcrum Therapeutics, Inc.COM447,326$3.26M0.5%−752,674−62.7%ReducedHistory
TRVITrevi Therapeutics, Inc.COM3,050,022$5.89M1.0%00.0%UnchangedHistory
MRNSMarinus Pharmaceuticals, Inc.COM NEW1,770,705$7.05M1.2%−1,386,098−43.9%ReducedHistory
LIANYLianBioSPONSORED ADS4,793,047$7.86M1.3%−585,294−10.9%ReducedHistory
MISTMilestone Pharmaceuticals Inc.COM2,208,812$8.75M1.5%−216,925−8.9%ReducedHistory
SVRASavara IncCOM6,351,531$9.84M1.7%+1,796,493+39.4%AddedHistory
PRVBProvention Bio, Inc.COM1,118,653$11.8M2.0%00.0%UnchangedHistory
Vectivbio Hldg AGH9060V101ORD SHS1,866,000$16.2M2.7%+1,866,000New–
ANNXAnnexon, Inc.COM3,220,050$16.6M2.8%00.0%UnchangedHistory
CABACabaletta Bio, Inc.COM1,895,285$17.5M3.0%+1,895,285NewHistory
MRUSMerus N.V.COM1,226,214$19.0M3.2%+1,226,214NewHistory
NVAXNovavax IncCOM NEW1,879,894$19.3M3.3%+1,879,894NewHistory
KALVKalVista Pharmaceuticals, Inc.COM2,916,667$19.7M3.3%+2,916,667NewHistory
PLRXPliant Therapeutics, Inc.COM1,080,000$20.9M3.5%00.0%UnchangedHistory
JBIOJade Biosciences, Inc.COM747,869$21.9M3.7%−86,058−10.3%ReducedHistory
DICEDICE Therapeutics, Inc.COM819,000$25.6M4.3%+54,021+7.1%AddedHistory
CELCCelcuity Inc.COM2,105,386$29.5M5.0%+2,105,386NewHistory
GHRSGH Research PLCORDINARY SHARES3,517,125$34.2M5.8%+183,971+5.5%AddedHistory
TERNTerns Pharmaceuticals, Inc.COM3,707,891$37.7M6.4%00.0%UnchangedHistory
COGTCogent Biosciences, Inc.COM4,038,117$46.7M7.9%00.0%UnchangedHistory
AXSMAxsome Therapeutics, Inc.COM670,718$51.7M8.7%+670,718NewHistory
ACRSAclaris Therapeutics, Inc.COM4,563,962$71.9M12.1%00.0%UnchangedHistory
VRDNViridian Therapeutics, Inc.COM2,699,865$78.9M13.3%+569,557+26.7%AddedHistory

Sold out since Q3 2022 (10)

Positions held at the end of Q3 2022 that are gone from this filing.

Positions of VR Adviser, LLC sold out since Q3 2022
SecurityClassShares in Q3 2022Value in Q3 2022% of portfolio in Q3 2022History
TCDATricida, Inc.COM9,050,064$94.8M14.6%History
RLMDRelmada Therapeutics, Inc.COM1,518,056$56.2M8.7%History
GOSSGossamer Bio, Inc.COM1,747,000$20.9M3.2%History
TILInstil Bio, Inc.COM4,105,779$19.9M3.1%History
AKUSAkouos, Inc.COM2,800,566$18.9M2.9%History
VTYXVentyx Biosciences, Inc.COM207,925$7.26M1.1%History
RXDXPrometheus Biosciences, Inc.COM121,663$7.18M1.1%History
ALTAltimmune, Inc.COM NEW369,306$4.72M0.7%History
IMCRImmunocore Holdings plcADS94,605$4.44M0.7%History
CLDXCelldex Therapeutics, Inc.COM NEW75,000$2.11M0.3%History