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Livermore
Livermore
ZHEN

Two Sigma Advisers, LP

SEC CIK
0001478735
Latest filing
Aug 14, 2026

Holdings in Q2 2021

Holdings as of Jun 30, 2021, filed Aug 16, 2021. Long positions only; changes compare share counts with Q1 2021.

Institution overview
Positions
2,418
−108 vs. Q1 2021
Portfolio value
$37.9B
+$1.51B (+4.1%) vs. Q1 2021
Filed
Aug 16, 2021
SEC
Holdings of Two Sigma Advisers, LP in Q2 2021
SecurityClassSharesValue% of portfolioShare changeActionHistory
DOMHDominari Holdings Inc.COM11,300$11.0K<0.1%+11,300NewHistory
Molecular Data Inc60852L106SPONSORED ADS11,300$11.0K<0.1%−28,200−71.4%Reduced–
FEDUFour Seasons Education (Cayman) Inc.ADR11,600$13.0K<0.1%+11,600NewHistory
TYMETyme Technologies, Inc.COM12,300$15.0K<0.1%+12,300NewHistory
FEEDENvue Medical, Inc.COM20,500$17.0K<0.1%+5,500+36.7%AddedHistory
FENGPhoenix New Media LtdSPONSORED ADS10,700$17.0K<0.1%−500−4.5%ReducedHistory
SSKNSTRATA Skin Sciences, Inc.COM NEW11,600$18.0K<0.1%+11,600NewHistory
TOVXTheriva Biologics, Inc.COM NEW33,700$20.0K<0.1%+33,700NewHistory
FSD Pharma Inc35954B206CL B SUB VTG12,100$21.0K<0.1%−18,900−61.0%Reduced–
China Jo-Jo Drugstores Inc16949A206COM NEW23,400$22.0K<0.1%−40,300−63.3%Reduced–
BDRLBlonder Tongue Laboratories IncCOM17,200$23.0K<0.1%−2,800−14.0%ReducedHistory
HURATuHURA Biosciences, Inc.COM10,114$23.0K<0.1%+10,114NewHistory
Laix Inc50736W105ADS13,400$25.0K<0.1%+200+1.5%Added–
GRDXGridAI Technologies Corp.COM33,200$27.0K<0.1%−14,000−29.7%ReducedHistory
COMSCOMSovereign Holding Corp.COM NEW12,000$28.0K<0.1%+12,000NewHistory
PTEPolarityte, Inc.COM27,129$28.0K<0.1%+27,129NewHistory
SNGXSoligenix, Inc.COM26,300$29.0K<0.1%+26,300NewHistory
TRIBTrinity Biotech PLCSPON ADR NEW10,300$30.0K<0.1%−6,700−39.4%ReducedHistory
PTNPalatin Technologies IncCOM PAR $ .0150,400$31.0K<0.1%−209,100−80.6%ReducedHistory
ALYAFAlithya Group incCL A SUB VTG11,300$32.0K<0.1%+11,300NewHistory
CTEKCynergistek, IncCOM15,700$32.0K<0.1%−11,600−42.5%ReducedHistory
WHWKWhitehawk Therapeutics, Inc.COM20,300$34.0K<0.1%+7,500+58.6%AddedHistory
NLS Pharmaceutics LtdH57830103SHS10,800$34.0K<0.1%+10,800New–
DYNTDynatronics CorpCOM NEW29,100$35.0K<0.1%+1,400+5.1%AddedHistory
BLNEBeeline Holdings, Inc.COM12,500$35.0K<0.1%+12,500NewHistory
Stealth Biotherapeutics Corp85789A105SPONSORED ADS22,700$35.0K<0.1%+22,700New–
BIOLBiolase, IncCOM NEW52,100$36.0K<0.1%+52,100NewHistory
SNESSenesTech, Inc.COM NEW22,100$36.0K<0.1%+5,100+30.0%AddedHistory
ASRVAmeriserv Financial IncCOM10,800$42.0K<0.1%+10,800NewHistory
LODEComstock Inc.COM NEW11,900$43.0K<0.1%−34,100−74.1%ReducedHistory
NCNANuCana plcSPONSORED ADR16,100$45.0K<0.1%−57,900−78.2%ReducedHistory
IZEAIZEA Worldwide, Inc.COM18,200$46.0K<0.1%+18,200NewHistory
EOCNGalmed Pharmaceuticals Ltd.SHS15,200$46.0K<0.1%−2,300−13.1%ReducedHistory
CHNRChina Natural Resources IncCOM30,400$47.0K<0.1%−14,900−32.9%ReducedHistory
AGRXAgile Therapeutics IncCOM37,000$49.0K<0.1%−292,300−88.8%ReducedHistory
Imv Inc44974L103COM22,600$49.0K<0.1%−48,300−68.1%Reduced–
PIXYShiftPixy, Inc.COM NEW20,800$49.0K<0.1%−20,800−50.0%ReducedHistory
PANLPangaea Logistics Solutions Ltd.SHS10,000$50.0K<0.1%+10,000NewHistory
STEXStreamex Corp.COM NEW13,100$51.0K<0.1%+2,900+28.4%AddedHistory
SONMDNA X, Inc.COM91,000$51.0K<0.1%−77,600−46.0%ReducedHistory
SYPRSypris Solutions IncCOM14,400$54.0K<0.1%−6,900−32.4%ReducedHistory
FURYFury Gold Mines LtdCOM44,989$54.0K<0.1%−67,500−60.0%ReducedHistory
RAVERave Restaurant Group, Inc.COM37,500$56.0K<0.1%−20,800−35.7%ReducedHistory
DMACDiaMedica Therapeutics Inc.COM NEW12,800$57.0K<0.1%+2,100+19.6%AddedHistory
Chiasma, Inc16706W102COM12,300$58.0K<0.1%−113,600−90.2%Reduced–
CRTDCreatd, Inc.COM16,600$62.0K<0.1%+5,900+55.1%AddedHistory
DAREDare Bioscience, Inc.COM33,000$62.0K<0.1%−91,600−73.5%ReducedHistory
YTRAYatra Online, Inc.ORD SHS28,100$64.0K<0.1%−3,900−12.2%ReducedHistory
CBUSCibus, Inc.COM16,300$66.0K<0.1%−300−1.8%ReducedHistory
SCPHscPharmaceuticals Inc.COM11,000$67.0K<0.1%−700−6.0%ReducedHistory
AUCATIF Holdings LtdSHS75,200$68.0K<0.1%−28,400−27.4%ReducedHistory
ACERAcer Therapeutics Inc.COM24,000$69.0K<0.1%+1,700+7.6%AddedHistory
Bio Green Med Solution, Inc.23254L603COM11,800$70.0K<0.1%+11,800New–
CRBPCorbus Pharmaceuticals Holdings, Inc.COM40,000$73.0K<0.1%−228,600−85.1%ReducedHistory
BCLIBrainstorm Cell Therapeutics Inc.COM NEW19,700$75.0K<0.1%−100,700−83.6%ReducedHistory
Catabasis Pharmaceuticals IN14875P206COM NEW36,200$76.0K<0.1%−49,000−57.5%Reduced–
O2MICRO International Limite67107W100SPONS ADR10,500$76.0K<0.1%−1,000−8.7%Reduced–
BYFCBroadway Financial Corp DECOM29,000$78.0K<0.1%−47,100−61.9%ReducedHistory
Xinyuan Real Estate Co Ltd98417P105SPONS ADR30,200$80.0K<0.1%−16,400−35.2%Reduced–
AMPGAmpliTech Group, Inc.COM NEW17,700$82.0K<0.1%+17,700NewHistory
CDTXCidara Therapeutics, Inc.COM40,594$82.0K<0.1%−48,200−54.3%ReducedHistory
Fednat Hldg Co31431B109COM19,700$82.0K<0.1%+3,000+18.0%Added–
RMNIRimini Street, Inc.COM13,600$84.0K<0.1%+13,600NewHistory
DNNDenison Mines Corp.COM72,800$87.0K<0.1%+72,800NewHistory
JGAurora Mobile LtdADS26,900$87.0K<0.1%−16,200−37.6%ReducedHistory
ARCArc Document Solutions, Inc.COM42,092$90.0K<0.1%−24,700−37.0%ReducedHistory
BCTXBriaCell Therapeutics Corp.COM NEW16,900$90.0K<0.1%+16,900NewHistory
VAIValor Energy IncCOM86,800$91.0K<0.1%−8,700−9.1%ReducedHistory
TONXTON Strategy CoCOM44,800$92.0K<0.1%−39,100−46.6%ReducedHistory
Davidstea Inc238661102COM21,500$94.0K<0.1%+5,800+36.9%Added–
VTVTvTv Therapeutics Inc.CL A42,300$96.0K<0.1%−156,200−78.7%ReducedHistory
CLPSCLPS IncCOM22,300$96.0K<0.1%−6,200−21.8%ReducedHistory
GERNGeron CorpCOM69,962$99.0K<0.1%−2,379,246−97.1%ReducedHistory
MDC Partners Inc.552697104CL A SUB VTG16,850$99.0K<0.1%−4,100−19.6%Reduced–
DYAIDyadic International IncCOM28,800$103.0K<0.1%+16,200+128.6%AddedHistory
CABACabaletta Bio, Inc.COM12,300$106.0K<0.1%−3,600−22.6%ReducedHistory
ETRNMidstream Co LLCCOM12,500$106.0K<0.1%−28,800−69.7%ReducedHistory
DHXDhi Group, Inc.COM31,700$107.0K<0.1%+12,800+67.7%AddedHistory
HOOKHOOKIPA Pharma Inc.COM11,700$107.0K<0.1%−11,600−49.8%ReducedHistory
RVSBRiverview Bancorp IncCOM15,300$108.0K<0.1%+15,300NewHistory
TRAWTraws Pharma, Inc.COM NEW15,633$108.0K<0.1%+15,633NewHistory
IDNIntellicheck, Inc.COM NEW13,000$109.0K<0.1%−800−5.8%ReducedHistory
ENZBEnzo Biochem IncCOM34,500$109.0K<0.1%+34,500NewHistory
PRVBProvention Bio, Inc.COM12,900$109.0K<0.1%−887,500−98.6%ReducedHistory
NTWKNetsol Technologies IncCOM PAR $.00123,400$110.0K<0.1%+23,400NewHistory
Aslan Pharmaceuticals Ltd04522R101ADS33,500$111.0K<0.1%+19,400+137.6%Added–
LSAKLesaka Technologies IncCOM NEW23,800$112.0K<0.1%+700+3.0%AddedHistory
USAUU.S. Gold Corp.COM NEW10,500$117.0K<0.1%−9,700−48.0%ReducedHistory
PCTIPC Tel IncCOM17,800$117.0K<0.1%+400+2.3%AddedHistory
TULPBloomia Holdings, Inc.COM NEW14,381$119.0K<0.1%+14,381NewHistory
LFVNLifevantage CorpCOM NEW16,300$120.0K<0.1%+16,300NewHistory
TANHTantech Holdings LtdCOM99,200$123.0K<0.1%+72,600+272.9%AddedHistory
CFRXCONTRAFECT CorpCOM NEW28,500$125.0K<0.1%+5,500+23.9%AddedHistory
GasLog Partners LPY2687W108UNIT LTD PTNRP34,200$126.0K<0.1%−9,500−21.7%Reduced–
Via Optronics AG91823Y109SPONSORED ADS11,400$128.0K<0.1%+11,400New–
Polymet MNG Corp731916409COM NEW35,610$129.0K<0.1%−133,400−78.9%Reduced–
Maverix Metals Inc57776F405COM NEW24,100$130.0K<0.1%00.0%Unchanged–
PHIOPhio Pharmaceuticals Corp.COM NEW57,600$130.0K<0.1%+28,100+95.3%AddedHistory
SCTLSocietal CDMO, Inc.COM57,300$132.0K<0.1%−93,600−62.0%ReducedHistory
VWTRVidler Water Resources, Inc.COM10,300$137.0K<0.1%−11,800−53.4%ReducedHistory

Sold out since Q1 2021 (439)

Positions held at the end of Q1 2021 that are gone from this filing.

The largest 100 of 439 by value last quarter.

Positions of Two Sigma Advisers, LP sold out since Q1 2021
SecurityClassShares in Q1 2021Value in Q1 2021% of portfolio in Q1 2021History
CSCOCisco Systems, Inc.Stock7,440,705$384.8M1.1%History
VZVerizon Communications IncStock2,756,463$160.3M0.4%History
FFord Motor CoStock12,614,600$154.5M0.4%History
PTONPeloton Interactive, Inc.CL A COM1,341,000$150.8M0.4%History
SHWSherwin Williams CoCOM195,799$144.5M0.4%History
BDXBecton Dickinson & CoStock510,200$124.1M0.3%History
RUNSunrun Inc.COM1,115,930$67.5M0.2%History
DHRDanaher CorpStock299,300$67.4M0.2%History
PENNPENN Entertainment, Inc.COM639,120$67.0M0.2%History
HDHome Depot, Inc.Stock210,400$64.2M0.2%History
BILIBilibili Inc.SPONS ADS REP Z572,800$61.3M0.2%History
ADBEAdobe Inc.Stock122,300$58.1M0.2%History
SJMJ M SMUCKER CoStock458,900$58.1M0.2%History
STZConstellation Brands, Inc.Stock251,700$57.4M0.2%History
Michaels Cos Inc59408Q106COM2,467,200$54.1M0.1%–
iShares Tr464287739U.S. REAL ES ETF560,300$51.5M0.1%–
YUMYum Brands IncStock434,800$47.0M0.1%History
PLUGPlug Power IncStock1,297,738$46.5M0.1%History
AMTAmerican Tower CorpREIT191,900$45.9M0.1%History
BKIBlack Knight, Inc.COM583,915$43.2M0.1%History
ORealty Income CorpREIT616,564$39.2M0.1%History
ETREntergy CorpCOM358,800$35.7M0.1%History
ADPAutomatic Data Processing IncStock183,214$34.5M0.1%History
Glu Mobile Inc379890106COM2,762,102$34.5M0.1%–
Grubhub Inc400110102COM568,800$34.1M0.1%–
iShares Tr464288752US HOME CONS ETF499,800$33.9M0.1%–
RTXRTX CorpStock425,495$32.9M0.1%History
SRESempraStock228,800$30.3M0.1%History
ESSEssex Property Trust, Inc.COM106,815$29.0M0.1%History
PSAPublic StorageCOM116,300$28.7M0.1%History
Colony Cap Inc New19626G108CL A COM4,412,820$28.6M0.1%–
GDDYGoDaddy Inc.CL A350,400$27.2M0.1%History
PYPLPayPal Holdings, Inc.Stock110,200$26.8M0.1%History
CLXClorox CoStock136,100$26.3M0.1%History
Vanguard Real Estate ETF922908553ETF265,800$24.4M0.1%–
Varian Med Sys Inc92220P105COM137,800$24.3M0.1%–
Five Prime Therapeutics Inc33830X104COM605,300$22.8M0.1%–
Cantel Med Corp138098108COM272,252$21.7M0.1%–
AZPNASPENTECH CorpCOM137,300$19.8M0.1%History
FNVFranco Nevada CorpStock135,400$17.0M<0.1%History
TXG10x Genomics, Inc.CL A COM93,700$17.0M<0.1%History
BMOBank of MontrealCOM187,319$16.7M<0.1%History
Aphria Inc03765K104COM895,800$16.5M<0.1%–
RGLDRoyal Gold IncStock147,264$15.8M<0.1%History
HRCHill-Rom Holdings, Inc.COM137,274$15.2M<0.1%History
AVBAvalonbay Communities IncCOM78,000$14.4M<0.1%History
WOLFWolfspeed, Inc.COM131,500$14.2M<0.1%History
SGENSeagen Inc.COM101,900$14.2M<0.1%History
NVRONevro CorpCOM97,700$13.6M<0.1%History
UDRUDR, Inc.COM308,100$13.5M<0.1%History
SVMK Inc78489X103COM737,500$13.5M<0.1%–
HMS Hldgs Corp40425J101COM358,814$13.3M<0.1%–
Cardtronics PLCG1991C105SHS CL A313,207$12.2M<0.1%–
XELXcel Energy IncStock182,200$12.1M<0.1%History
FBINFortune Brands Innovations, Inc.COM126,012$12.1M<0.1%History
State Street SPDR S&P Biotech ETF78464A870ETF88,100$12.0M<0.1%–
MELIMercadolibre IncCOM7,600$11.2M<0.1%History
IRBTiRobot CorpCOM91,408$11.2M<0.1%History
Corelogic Inc21871D103COM140,900$11.2M<0.1%–
WMBWilliams Companies, Inc.COM470,900$11.2M<0.1%History
CMCanadian Imperial Bank of CommerceCOM107,300$10.5M<0.1%History
TXNTexas Instruments IncStock55,300$10.5M<0.1%History
NEOGNeogen CorpCOM116,521$10.4M<0.1%History
Perspecta Inc715347100COM356,300$10.4M<0.1%–
CZRCaesars Entertainment, Inc.COM115,700$10.1M<0.1%History
OGEOGE Energy Corp.COM308,500$9.98M<0.1%History
BLDRBuilders FirstSource, Inc.Stock209,731$9.72M<0.1%History
STWDStarwood Property Trust, Inc.COM369,116$9.13M<0.1%History
GDSGDS Holdings LtdSPONSORED ADS112,400$9.12M<0.1%History
CSLCarlisle Companies IncCOM52,492$8.64M<0.1%History
TDGTransDigm Group INCCOM13,848$8.14M<0.1%History
ZNGAZynga IncCL A788,773$8.05M<0.1%History
DDominion Energy, IncStock102,400$7.78M<0.1%History
HIIHuntington Ingalls Industries, Inc.COM37,300$7.68M<0.1%History
WEXWEX Inc.COM36,680$7.67M<0.1%History
TMXTerminix Global Holdings IncCOM148,800$7.09M<0.1%History
OUTOUTFRONT Media Inc.COM320,147$6.99M<0.1%History
AQUAEvoqua Water Technologies Corp.COM265,600$6.99M<0.1%History
NEENextera Energy IncStock92,200$6.97M<0.1%History
MTHMeritage Homes CORPCOM74,000$6.80M<0.1%History
MTGMgic Investment CorpCOM475,455$6.58M<0.1%History
MKTXMarketaxess Holdings IncCOM13,100$6.52M<0.1%History
CAGConagra Brands Inc.Stock172,900$6.50M<0.1%History
DISHDISH Network CORPCL A169,914$6.15M<0.1%History
RACEFerrari N.V.COM29,200$6.11M<0.1%History
NOVASunnova Energy International Inc.COM149,300$6.09M<0.1%History
Realpage Inc75606N109COM69,284$6.04M<0.1%–
SEDGSolaredge Technologies, Inc.COM20,800$5.98M<0.1%History
USBUS Bancorp DECOM NEW107,689$5.96M<0.1%History
VFFVillage Farms International, Inc.COM447,300$5.92M<0.1%History
HZNPHorizon Therapeutics Public Ltd CoSHS62,600$5.76M<0.1%History
Seacor Holdings Inc811904101COM140,490$5.72M<0.1%–
SBGISinclair, Inc.CL A192,300$5.63M<0.1%History
XPOXPO, Inc.COM44,551$5.49M<0.1%History
FULFuller H B CoStock83,100$5.23M<0.1%History
PRFTPerficient IncCOM85,348$5.01M<0.1%History
QTWOQ2 Holdings, Inc.COM49,900$5.00M<0.1%History
ACADAcadia Pharmaceuticals IncCOM189,500$4.89M<0.1%History
PODDInsulet CorpStock18,500$4.83M<0.1%History
LACLithium Americas Corp.COM NEW298,000$4.79M<0.1%History