| Date | Insider | Title | Code | Shares | Price | Value |
|---|---|---|---|---|---|---|
| Aug 17, 2026 | Ali Faraz | Chief Executive Officer | S | 7,406 | $0.7097 | $5.26K |
| Aug 17, 2026 | Ali Faraz | Chief Executive Officer | S | 5,020 | $0.7097 | $3.56K |
| Aug 17, 2026 | Ali Faraz | Chief Executive Officer | S | 3,969 | $0.7098 | $2.82K |
| Aug 17, 2026 | Ali Faraz | Chief Executive Officer | S | 5,837 | $0.7097 | $4.14K |
| Aug 17, 2026 | Tingley Whittemore | Chief Medical Officer | S | 2,279 | $0.7098 | $1.62K |
| Aug 17, 2026 | Tingley Whittemore | Chief Medical Officer | S | 1,871 | $0.7098 | $1.33K |
| Aug 17, 2026 | Tingley Whittemore | Chief Medical Officer | S | 1,637 | $0.7098 | $1.16K |
| Aug 17, 2026 | Tingley Whittemore | Chief Medical Officer | S | 1,637 | $0.7098 | $1.16K |
| Jul 13, 2026 | Hyllengren Eric J | Chief Financial Officer | A | 1,650,000 | $0.0000 | $0.00 |
| May 28, 2026 | Burroughs Amy L. | Director | A | 120,000 | $0.0000 | $0.00 |
| May 28, 2026 | Lee June | Director | A | 120,000 | $0.0000 | $0.00 |
| May 28, 2026 | Parschauer Karah Herdman | Director | A | 120,000 | $0.0000 | $0.00 |
| May 28, 2026 | Srivastava Deepak | Director | A | 120,000 | $0.0000 | $0.00 |
| May 28, 2026 | Stehman-Breen Catherine | Director | A | 120,000 | $0.0000 | $0.00 |
| May 28, 2026 | Walsh Jeffrey T. | Director | A | 120,000 | $0.0000 | $0.00 |
| May 28, 2026 | Williams R Sanders | Director | A | 120,000 | $0.0000 | $0.00 |
| May 18, 2026 | Higa Tomohiro | SVP, Finance | S | 1,485 | $0.7932 | $1.18K |
| May 18, 2026 | Tingley Whittemore | Chief Medical Officer | S | 3,121 | $0.7936 | $2.48K |
| May 18, 2026 | Ali Faraz | Chief Executive Officer | S | 3,390 | $0.7934 | $2.69K |
| Feb 25, 2026 | COLUMN GROUP III GP, LP | 10% Owner | S | 1,862,545 | $0.5624 | $1.05M |
| Feb 25, 2026 | COLUMN GROUP III GP, LP | 10% Owner | S | 1,649,281 | $0.5624 | $927.55K |
| Feb 24, 2026 | COLUMN GROUP III GP, LP | 10% Owner | S | 349,212 | $0.6153 | $214.87K |
| Feb 24, 2026 | COLUMN GROUP III GP, LP | 10% Owner | S | 309,228 | $0.6153 | $190.27K |
| Feb 23, 2026 | COLUMN GROUP III GP, LP | 10% Owner | S | 162,291 | $0.5972 | $96.92K |
| Feb 23, 2026 | COLUMN GROUP III GP, LP | 10% Owner | S | 143,709 | $0.5972 | $85.82K |
| Feb 20, 2026 | COLUMN GROUP III GP, LP | 10% Owner | S | 277,769 | $0.6149 | $170.80K |
| Feb 20, 2026 | COLUMN GROUP III GP, LP | 10% Owner | S | 245,965 | $0.6149 | $151.24K |
| Feb 17, 2026 | Tingley Whittemore | Chief Medical Officer | S | 1,876 | $0.6431 | $1.21K |
| Feb 17, 2026 | Tingley Whittemore | Chief Medical Officer | S | 1,642 | $0.6432 | $1.06K |
| Feb 17, 2026 | Tingley Whittemore | Chief Medical Officer | S | 1,642 | $0.6432 | $1.06K |
| Feb 17, 2026 | Ali Faraz | Chief Executive Officer | S | 5,032 | $0.6430 | $3.23K |
| Feb 17, 2026 | Ali Faraz | Chief Executive Officer | S | 3,979 | $0.6431 | $2.56K |
| Feb 17, 2026 | Ali Faraz | Chief Executive Officer | S | 5,851 | $0.6430 | $3.76K |
| Feb 17, 2026 | Higa Tomohiro | SVP, Finance | S | 2,022 | $0.6431 | $1.30K |
| Feb 17, 2026 | Higa Tomohiro | SVP, Finance | S | 836 | $0.6434 | $537.00 |
| Feb 17, 2026 | Higa Tomohiro | SVP, Finance | S | 611 | $0.6434 | $393.00 |
| Feb 11, 2026 | COLUMN GROUP III GP, LP | 10% Owner | S | 2,151,458 | $0.6808 | $1.46M |
| Feb 11, 2026 | COLUMN GROUP III GP, LP | 10% Owner | S | 1,905,115 | $0.6808 | $1.30M |
| Feb 10, 2026 | COLUMN GROUP III GP, LP | 10% Owner | S | 182,295 | $0.8161 | $148.77K |
| Feb 10, 2026 | COLUMN GROUP III GP, LP | 10% Owner | S | 161,422 | $0.8161 | $131.74K |
| Feb 3, 2026 | Tingley Whittemore | Chief Medical Officer | A | 318,500 | $0.0000 | $0.00 |
| Feb 3, 2026 | Tingley Whittemore | Chief Medical Officer | A | 48,750 | $0.0000 | $0.00 |
| Feb 3, 2026 | Ali Faraz | Chief Executive Officer | A | 952,250 | $0.0000 | $0.00 |
| Feb 3, 2026 | Ali Faraz | Chief Executive Officer | A | 158,600 | $0.0000 | $0.00 |
| Feb 3, 2026 | Higa Tomohiro | SVP, Finance | A | 175,500 | $0.0000 | $0.00 |
| Feb 3, 2026 | Higa Tomohiro | SVP, Finance | A | 29,250 | $0.0000 | $0.00 |
| Nov 17, 2025 | Ali Faraz | Chief Executive Officer | S | 3,126 | $1.3300 | $4.16K |
| Nov 17, 2025 | Higa Tomohiro | SVP, Finance | S | 1,367 | $1.3300 | $1.82K |
| Nov 17, 2025 | Tingley Whittemore | Chief Medical Officer | S | 2,877 | $1.3300 | $3.83K |
| Aug 18, 2025 | Ali Faraz | Chief Executive Officer | S | 4,920 | $1.2530 | $6.16K |