| Date | Insider | Title | Code | Shares | Price | Value |
|---|---|---|---|---|---|---|
| Aug 7, 2026 | Agresta Samuel | Chief Medical Officer | A | 131,396 | – | – |
| Aug 7, 2026 | Agresta Samuel | Chief Medical Officer | D | 131,396 | – | – |
| Aug 7, 2026 | Agresta Samuel | Chief Medical Officer | A | 18,588 | – | – |
| Aug 7, 2026 | Agresta Samuel | Chief Medical Officer | D | 18,588 | – | – |
| Aug 7, 2026 | Agresta Samuel | Chief Medical Officer | A | 50,000 | $0.0000 | $0.00 |
| Aug 7, 2026 | Hartley Dylan | Chief Scientific Officer | A | 137,603 | – | – |
| Aug 7, 2026 | Hartley Dylan | Chief Scientific Officer | D | 137,603 | – | – |
| Aug 7, 2026 | Hartley Dylan | Chief Scientific Officer | A | 50,000 | $0.0000 | $0.00 |
| Aug 7, 2026 | Leverone Jason A. | Chief Financial Officer | A | 130,611 | – | – |
| Aug 7, 2026 | Leverone Jason A. | Chief Financial Officer | D | 130,611 | – | – |
| Aug 7, 2026 | Leverone Jason A. | Chief Financial Officer | A | 5,322 | – | – |
| Aug 7, 2026 | Leverone Jason A. | Chief Financial Officer | D | 5,322 | – | – |
| Aug 7, 2026 | Leverone Jason A. | Chief Financial Officer | A | 5,781 | – | – |
| Aug 7, 2026 | Leverone Jason A. | Chief Financial Officer | D | 5,781 | – | – |
| Aug 7, 2026 | Leverone Jason A. | Chief Financial Officer | A | 50,000 | $0.0000 | $0.00 |
| Aug 7, 2026 | Saccomano Nicholas A | President and CEO | A | 542,232 | – | – |
| Aug 7, 2026 | Saccomano Nicholas A | President and CEO | D | 542,232 | – | – |
| Aug 7, 2026 | Saccomano Nicholas A | President and CEO | A | 16,898 | – | – |
| Aug 7, 2026 | Saccomano Nicholas A | President and CEO | D | 16,898 | – | – |
| Aug 7, 2026 | Saccomano Nicholas A | President and CEO | A | 8,449 | – | – |
| Aug 7, 2026 | Saccomano Nicholas A | President and CEO | D | 8,449 | – | – |
| Aug 7, 2026 | Saccomano Nicholas A | President and CEO | A | 1,485 | – | – |
| Aug 7, 2026 | Saccomano Nicholas A | President and CEO | D | 1,485 | – | – |
| Aug 7, 2026 | Saccomano Nicholas A | President and CEO | A | 2,359 | – | – |
| Aug 7, 2026 | Saccomano Nicholas A | President and CEO | D | 2,359 | – | – |
| Aug 7, 2026 | Saccomano Nicholas A | President and CEO | A | 150,000 | $0.0000 | $0.00 |
| Aug 7, 2026 | Carruthers R Michael | Director | A | 22,350 | $0.0000 | $0.00 |
| Aug 7, 2026 | Jansen Valerie Malyvanh | Director | A | 22,350 | $0.0000 | $0.00 |
| Aug 7, 2026 | GREY MICHAEL G | Director | A | 22,350 | $0.0000 | $0.00 |
| Aug 7, 2026 | Manke Isaac | Director | A | 15,300 | – | – |
| Aug 7, 2026 | Manke Isaac | Director | D | 15,300 | – | – |
| Aug 7, 2026 | Manke Isaac | Director | A | 300,000 | $0.0000 | $0.00 |
| Aug 7, 2026 | Phillips Andrew John | Director | A | 22,350 | $0.0000 | $0.00 |
| Aug 7, 2026 | Ratcliffe Liam | Director | A | 22,350 | $0.0000 | $0.00 |
| Aug 7, 2026 | Mathers Edward T | Director | A | 22,350 | $0.0000 | $0.00 |
| Jun 22, 2026 | Leverone Jason A. | Chief Financial Officer | S | 303 | $4.3963 | $1.33K |
| Jun 22, 2026 | Saccomano Nicholas A | President and CEO | S | 86 | $4.3963 | $378.00 |
| Jun 4, 2026 | Carruthers R Michael | Director | A | 7,650 | $0.0000 | $0.00 |
| Jun 4, 2026 | Jansen Valerie Malyvanh | Director | A | 7,650 | $0.0000 | $0.00 |
| Jun 4, 2026 | GREY MICHAEL G | Director | A | 7,650 | $0.0000 | $0.00 |
| Jun 4, 2026 | Phillips Andrew John | Director | A | 7,650 | $0.0000 | $0.00 |
| Jun 4, 2026 | Ratcliffe Liam | Director | A | 1,275 | $0.0000 | $0.00 |
| Jun 4, 2026 | Mathers Edward T | Director | A | 7,650 | $0.0000 | $0.00 |
| Apr 1, 2026 | Hartley Dylan | Chief Scientific Officer | A | 110,000 | $0.0000 | $0.00 |
| Apr 1, 2026 | Leverone Jason A. | Chief Financial Officer | A | 110,000 | $0.0000 | $0.00 |
| Apr 1, 2026 | Agresta Samuel | Chief Medical Officer | A | 110,000 | $0.0000 | $0.00 |
| Apr 1, 2026 | Saccomano Nicholas A | President and CEO | A | 330,000 | $0.0000 | $0.00 |
| Mar 31, 2026 | Ratcliffe Liam | Director | A | 15,300 | $0.0000 | $0.00 |
| Mar 23, 2026 | Leverone Jason A. | Chief Financial Officer | S | 301 | $4.1565 | $1.25K |
| Mar 23, 2026 | Saccomano Nicholas A | President and CEO | S | 86 | $4.1565 | $357.00 |