| Date | Insider | Title | Code | Shares | Price | Value |
|---|---|---|---|---|---|---|
| Aug 18, 2026 | Farquhar John C.M. | Chief Executive Officer | S | 32,676 | $45.0000 | $1.47M |
| Aug 17, 2026 | Rogers Campbell | Chief Medical Officer | M | 9,219 | $0.0000 | $0.00 |
| Aug 17, 2026 | Rogers Campbell | Chief Medical Officer | S | 9,219 | $41.2300 | $380.10K |
| Aug 17, 2026 | Rogers Campbell | Chief Medical Officer | M | 9,219 | $19.0000 | $175.16K |
| Aug 14, 2026 | Farquhar John C.M. | Chief Executive Officer | S | 15,560 | $39.0600 | $607.77K |
| Aug 10, 2026 | Farquhar John C.M. | Chief Executive Officer | S | 22,562 | $28.3100 | $638.73K |
| Aug 7, 2026 | Farquhar John C.M. | Chief Executive Officer | F | 1,904 | $28.8200 | $54.87K |
| Aug 7, 2026 | Rogers Campbell | Chief Medical Officer | F | 637 | $28.8200 | $18.36K |
| Aug 7, 2026 | Verghese Vikram | Chief Financial Officer | F | 473 | $28.8200 | $13.63K |
| Aug 7, 2026 | Jones Marie L. | Chief Accounting Officer | F | 82 | $28.8200 | $2.36K |
| Aug 6, 2026 | Farquhar John C.M. | Chief Executive Officer | F | 5,847 | $27.1900 | $158.98K |
| Aug 6, 2026 | Rogers Campbell | Chief Medical Officer | F | 1,635 | $27.1900 | $44.45K |
| Aug 6, 2026 | Verghese Vikram | Chief Financial Officer | F | 1,537 | $27.1900 | $41.79K |
| Aug 6, 2026 | Jones Marie L. | Chief Accounting Officer | F | 486 | $27.1900 | $13.21K |
| Jul 30, 2026 | Farquhar John C.M. | Chief Executive Officer | M | 9,737 | $0.0000 | $0.00 |
| Jul 30, 2026 | Farquhar John C.M. | Chief Executive Officer | M | 2,789 | $0.0000 | $0.00 |
| Jul 30, 2026 | Farquhar John C.M. | Chief Executive Officer | M | 18,694 | $0.0000 | $0.00 |
| Jul 30, 2026 | Farquhar John C.M. | Chief Executive Officer | M | 9,737 | $9.5800 | $93.28K |
| Jul 30, 2026 | Farquhar John C.M. | Chief Executive Officer | M | 18,694 | $2.2200 | $41.50K |
| Jul 30, 2026 | Farquhar John C.M. | Chief Executive Officer | M | 2,789 | $8.3300 | $23.23K |
| Jul 27, 2026 | Verghese Vikram | Chief Financial Officer | M | 22,522 | $0.0000 | $0.00 |
| Jul 27, 2026 | Verghese Vikram | Chief Financial Officer | M | 22,522 | $2.2200 | $50.00K |
| Jul 24, 2026 | Lightcap Jeffrey C | Director | M | 47,420 | $0.0000 | $0.00 |
| Jul 24, 2026 | Lightcap Jeffrey C | Director | M | 47,420 | $19.0000 | $900.98K |
| Jul 22, 2026 | BARABE TIMOTHY C | Director | M | 3,710 | $0.0000 | $0.00 |
| Jul 22, 2026 | BARABE TIMOTHY C | Director | M | 3,710 | $19.0000 | $70.49K |
| Jul 21, 2026 | Verghese Vikram | Chief Financial Officer | M | 22,522 | $0.0000 | $0.00 |
| Jul 21, 2026 | Verghese Vikram | Chief Financial Officer | M | 22,522 | $2.2200 | $50.00K |
| Jul 17, 2026 | BARABE TIMOTHY C | Director | M | 5,000 | $0.0000 | $0.00 |
| Jul 17, 2026 | BARABE TIMOTHY C | Director | M | 5,000 | $19.0000 | $95.00K |
| Jul 15, 2026 | Rogers Campbell | Chief Medical Officer | M | 9,219 | $0.0000 | $0.00 |
| Jul 15, 2026 | Rogers Campbell | Chief Medical Officer | S | 9,219 | $25.7200 | $237.11K |
| Jul 15, 2026 | Rogers Campbell | Chief Medical Officer | M | 9,219 | $19.0000 | $175.16K |
| Jul 10, 2026 | Farquhar John C.M. | Chief Executive Officer | S | 22,562 | $27.7500 | $626.10K |
| Jul 8, 2026 | WELDON WILLIAM C | Director | M | 17,123 | $0.0000 | $0.00 |
| Jul 8, 2026 | WELDON WILLIAM C | Director | M | 17,123 | $0.0000 | $0.00 |
| Jul 8, 2026 | WELDON WILLIAM C | Director | M | 17,123 | $0.0000 | $0.00 |
| Jul 8, 2026 | WELDON WILLIAM C | Director | M | 17,123 | $8.3300 | $142.63K |
| Jul 8, 2026 | WELDON WILLIAM C | Director | M | 17,123 | $8.3300 | $142.63K |
| Jul 8, 2026 | WELDON WILLIAM C | Director | M | 17,123 | $8.3300 | $142.63K |
| Jun 24, 2026 | Farquhar John C.M. | Chief Executive Officer | S | 38,900 | $35.0000 | $1.36M |
| Jun 16, 2026 | Tansey Casey M | Director | A | 16,075 | $32.0500 | $515.20K |
| Jun 16, 2026 | Riley Wayne Joseph | Director | A | 16,075 | $32.0500 | $515.20K |
| Jun 16, 2026 | Cullivan Julie A | Director | A | 16,075 | $32.0500 | $515.20K |
| Jun 16, 2026 | Lightcap Jeffrey C | Director | A | 16,075 | $32.0500 | $515.20K |
| Jun 16, 2026 | BARABE TIMOTHY C | Director | A | 16,075 | $32.0500 | $515.20K |
| Jun 16, 2026 | WELDON WILLIAM C | Director | A | 16,075 | $32.0500 | $515.20K |
| Jun 15, 2026 | Rogers Campbell | Chief Medical Officer | M | 10,000 | $0.0000 | $0.00 |
| Jun 15, 2026 | Rogers Campbell | Chief Medical Officer | M | 10,000 | $2.2200 | $22.20K |
| Jun 10, 2026 | Farquhar John C.M. | Chief Executive Officer | S | 22,562 | $28.5000 | $643.02K |